Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
1R01HL062615-01A1
Application #
6042827
Study Section
Surgery, Anesthesiology and Trauma Study Section (SAT)
Project Start
1999-09-30
Project End
2004-08-31
Budget Start
1999-09-30
Budget End
2000-08-31
Support Year
1
Fiscal Year
1999
Total Cost
Indirect Cost
Name
Massachusetts General Hospital
Department
Type
DUNS #
City
Boston
State
MA
Country
United States
Zip Code
02199
Aidlen, Jeremy T; Nazarey, Pradeep P; Kinane, T Bernard et al. (2007) Retinoic acid-mediated differentiation protects against nitrofen-induced apoptosis. Birth Defects Res B Dev Reprod Toxicol 80:406-16
Kling, David E; Brandon, Kirra L; Sollinger, Christina A et al. (2006) Distribution of ERK1/2 and ERK3 during normal rat fetal lung development. Anat Embryol (Berl) 211:139-53
Kling, D E; Aidlen, J T; Fisher, J C et al. (2005) Nitrofen induces a redox-dependent apoptosis associated with increased p38 activity in P19 teratocarcinoma cells. Toxicol In Vitro 19:1-10
Schnitzer, Jay J (2004) Control and regulation of pulmonary hypoplasia associated with congenital diaphragmatic hernia. Semin Pediatr Surg 13:37-43
Kling, David E; Lorenzo, Hans K; Trbovich, Alexander M et al. (2002) MEK-1/2 inhibition reduces branching morphogenesis and causes mesenchymal cell apoptosis in fetal rat lungs. Am J Physiol Lung Cell Mol Physiol 282:L370-8
Kling, D E; Narra, V; Islam, S et al. (2001) Decreased mitogen activated protein kinase activities in congenital diaphragmatic hernia-associated pulmonary hypoplasia. J Pediatr Surg 36:1490-6