Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL073762-02
Application #
6767598
Study Section
Special Emphasis Panel (ZHL1-CSR-J (M2))
Program Officer
Thomas, John
Project Start
2003-07-01
Project End
2007-06-30
Budget Start
2004-07-01
Budget End
2005-06-30
Support Year
2
Fiscal Year
2004
Total Cost
$521,331
Indirect Cost
Name
Washington University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
068552207
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
Gregory, Alyssa D; Capoccia, Benjamin J; Woloszynek, Jill R et al. (2010) Systemic levels of G-CSF and interleukin-6 determine the angiogenic potential of bone marrow resident monocytes. J Leukoc Biol 88:123-31
Capoccia, Benjamin J; Robson, Debra L; Levac, Krysta D et al. (2009) Revascularization of ischemic limbs after transplantation of human bone marrow cells with high aldehyde dehydrogenase activity. Blood 113:5340-51
Shaked, Yuval; Tang, Terence; Woloszynek, Jill et al. (2009) Contribution of granulocyte colony-stimulating factor to the acute mobilization of endothelial precursor cells by vascular disrupting agents. Cancer Res 69:7524-8
Capoccia, Benjamin J; Gregory, Alyssa D; Link, Daniel C (2008) Recruitment of the inflammatory subset of monocytes to sites of ischemia induces angiogenesis in a monocyte chemoattractant protein-1-dependent fashion. J Leukoc Biol 84:760-8
Shepherd, Rebecca M; Capoccia, Benjamin J; Devine, Steven M et al. (2006) Angiogenic cells can be rapidly mobilized and efficiently harvested from the blood following treatment with AMD3100. Blood 108:3662-7
Capoccia, Benjamin J; Shepherd, Rebecca M; Link, Daniel C (2006) G-CSF and AMD3100 mobilize monocytes into the blood that stimulate angiogenesis in vivo through a paracrine mechanism. Blood 108:2438-45
Guven, Hasan; Shepherd, Rebecca M; Bach, Richard G et al. (2006) The number of endothelial progenitor cell colonies in the blood is increased in patients with angiographically significant coronary artery disease. J Am Coll Cardiol 48:1579-87