Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
3R01HL075187-01S1
Application #
6866062
Study Section
Special Emphasis Panel (ZHL1)
Program Officer
Denholm, Elizabeth M
Project Start
2003-09-22
Project End
2007-07-31
Budget Start
2004-05-01
Budget End
2004-07-31
Support Year
1
Fiscal Year
2004
Total Cost
$31,386
Indirect Cost
Name
La Biomed Research Institute/ Harbor UCLA Medical Center
Department
Type
DUNS #
069926962
City
Torrance
State
CA
Country
United States
Zip Code
90502
Sun, Miranda; Ramchandran, Ramaswamy; Chen, Jiwang et al. (2016) Smooth Muscle Insulin-Like Growth Factor-1 Mediates Hypoxia-Induced Pulmonary Hypertension in Neonatal Mice. Am J Respir Cell Mol Biol 55:779-791
Yang, Qiwei; Sun, Miranda; Ramchandran, Ramaswamy et al. (2015) IGF-1 signaling in neonatal hypoxia-induced pulmonary hypertension: Role of epigenetic regulation. Vascul Pharmacol 73:20-31
Chen, Tianji; Zhou, Guofei; Zhou, Qiyuan et al. (2015) Loss of microRNA-17?92 in smooth muscle cells attenuates experimental pulmonary hypertension via induction of PDZ and LIM domain 5. Am J Respir Crit Care Med 191:678-92
Zhou, Guofei; Chen, Tianji; Raj, J Usha (2015) MicroRNAs in pulmonary arterial hypertension. Am J Respir Cell Mol Biol 52:139-51
Ramchandran, Ramaswamy; Raghavan, Aarti; Geenen, David et al. (2014) PKG-1? leucine zipper domain defect increases pulmonary vascular tone: implications in hypoxic pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol 307:L537-44
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Ye, Liping; Liu, Juan; Liu, Huixia et al. (2013) Sulfhydryl-dependent dimerization of soluble guanylyl cyclase modulates the relaxation of porcine pulmonary arteries to nitric oxide. Pflugers Arch 465:333-41
Kang, Kang; Peng, Xiao; Zhang, Xiaoying et al. (2013) MicroRNA-124 suppresses the transactivation of nuclear factor of activated T cells by targeting multiple genes and inhibits the proliferation of pulmonary artery smooth muscle cells. J Biol Chem 288:25414-27
Yang, Q; Dahl, M J; Albertine, K H et al. (2013) Role of histone deacetylases in regulation of phenotype of ovine newborn pulmonary arterial smooth muscle cells. Cell Prolif 46:654-64
Ibe, Joyce Christina F; Zhou, Qiyuan; Chen, Tianji et al. (2013) Adenosine monophosphate-activated protein kinase is required for pulmonary artery smooth muscle cell survival and the development of hypoxic pulmonary hypertension. Am J Respir Cell Mol Biol 49:609-18

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