|
Kharade, Sujay V; Kurata, Haruto; Bender, Aaron M et al. (2018) Discovery, Characterization, and Effects on Renal Fluid and Electrolyte Excretion of the Kir4.1 Potassium Channel Pore Blocker, VU0134992. Mol Pharmacol 94:926-937
|
|
Huang, Hui; Kuenze, Georg; Smith, Jarrod A et al. (2018) Mechanisms of KCNQ1 channel dysfunction in long QT syndrome involving voltage sensor domain mutations. Sci Adv 4:eaar2631
|
|
Sivley, R Michael; Sheehan, Jonathan H; Kropski, Jonathan A et al. (2018) Three-dimensional spatial analysis of missense variants in RTEL1 identifies pathogenic variants in patients with Familial Interstitial Pneumonia. BMC Bioinformatics 19:18
|
|
Schwartz, Peter J; Crotti, Lia; George Jr, Alfred L (2018) Modifier genes for sudden cardiac death. Eur Heart J 39:3925-3931
|
|
Sivley, R Michael; Dou, Xiaoyi; Meiler, Jens et al. (2018) Comprehensive Analysis of Constraint on the Spatial Distribution of Missense Variants in Human Protein Structures. Am J Hum Genet 102:415-426
|
|
Yang, Zhenlin; Han, Shuo; Keller, Max et al. (2018) Structural basis of ligand binding modes at the neuropeptide Y Y1 receptor. Nature 556:520-524
|
|
Xia, Yan; Fischer, Axel W; Teixeira, Pedro et al. (2018) Integrated Structural Biology for ?-Helical Membrane Protein Structure Determination. Structure 26:657-666.e2
|
|
Vanoye, Carlos G; Desai, Reshma R; Fabre, Katarina L et al. (2018) High-Throughput Functional Evaluation of KCNQ1 Decrypts Variants of Unknown Significance. Circ Genom Precis Med 11:e002345
|
|
Kharade, Sujay V; Sheehan, Jonathan H; Figueroa, Eric E et al. (2017) Pore Polarity and Charge Determine Differential Block of Kir1.1 and Kir7.1 Potassium Channels by Small-Molecule Inhibitor VU590. Mol Pharmacol 92:338-346
|
|
Teixeira, Pedro L; Mendenhall, Jeff L; Heinze, Sten et al. (2017) Membrane protein contact and structure prediction using co-evolution in conjunction with machine learning. PLoS One 12:e0177866
|
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