Adolescence is a time of great susceptibility to sleep problems. A three-part approach to the assessment of sleeping and waking behavior in adolescents is planned with the following goals: to assess the mcehanisms of sleep function and the role of nocturnal sleep in achieving optimal alertness in adolescents; to evaluate the impact of daytime sleepiness on education and to investigate the efficacy of intervention; to achieve an estimate of the prevalence of specific sleep disorders in adolescents and to evaluate therapeutic interventions, as well as to begin the search for a biochemical marker of narcolepsy in adolescents """"""""at risk"""""""" for the disorder. Mechanisms of sleep function and the role of nocturnal sleep in adolescents will be assessed in a number of sleep laboratory studies. These studies include an evaluation of the role of slow wave sleep in young and older adolescents, assessment of the relevance of sleep continuity, the effects of sleep length, napping, and the role of circadian rhythms. Educational impact will be determined from survey data and primarily from remote video observational studies in the classroom. In addition, one experiment is designed to assess the effectiveness of an educational program in junior high school students. The final series of project will include polysomnographic verification of sleep complaints, nonpharmacologic treatment of specific sleep disorders, and a longitudinal assessment of children """"""""at risk"""""""" to develop narcolepsy.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Project (R01)
Project #
5R01MH031845-09
Application #
3375261
Study Section
(PCBB)
Project Start
1985-06-01
Project End
1989-05-31
Budget Start
1987-08-01
Budget End
1988-05-31
Support Year
9
Fiscal Year
1987
Total Cost
Indirect Cost
Name
Stanford University
Department
Type
Schools of Medicine
DUNS #
800771545
City
Stanford
State
CA
Country
United States
Zip Code
94305
Carskadon, M A; Dement, W C (1987) Daytime sleepiness: quantification of a behavioral state. Neurosci Biobehav Rev 11:307-17