Four studies involving assessment and intervention with preterm infants are proposed:
The aim of Study I is to establish the reliability and validity of a new longitudinal neurobehavioral assessment procedure for preterm infants of 24 weeks conceptional age and up. Additionally, this study will document systematically the ontogeny of the expanding behavioral repertoire of preterm infants as they grow to term. Study II will assess whether waterbed flotation facilitates the organization of preterm infants' sleep and motility which are typically quite disorganized in these infants. Comparisons will be made between the infants' sleep and motility patterns on the standard incubator mattress, a nonoscillating waterbed, a continuously oscillating waterbed and a waterbed that oscillates intermittently either in the pattern of a maternal biological rhythm or at arbitrary intervals. Visual observations of sleep-wake states and the quality of the infants' movements will be made together with Vitalog recordings of the frequency and distribution of infant activity. Study III will determine whether waterbeds can increase both the duration and soundness of sleep and attenuate the restlessness and erratic motility frequently seen in infants on stimulant drugs for the treatment of apnea. The same protocol of observations and recordings will be used as in Study II. Study IV is a longitudinal intervention study which is to test whether compensatory movement stimulation through waterbed flotation enhances the development of preterm infants. Assessment of the sleep and motility, of neurobehavioral and other developmental functioning of randomly assigned experimental and control subjects will be made longitudinally up to 6 months post-term. The relevance of the studies' findings to the improvement of clinical services to preterm infants and the direct linkages to and collaboration with the infants' health care providers and the channels of dissemination of the research findings are outlined.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Project (R01)
Project #
5R01MH036884-05
Application #
3375951
Study Section
(SRC)
Project Start
1982-09-20
Project End
1989-11-30
Budget Start
1986-12-01
Budget End
1987-11-30
Support Year
5
Fiscal Year
1987
Total Cost
Indirect Cost
Name
Stanford University
Department
Type
Schools of Medicine
DUNS #
800771545
City
Stanford
State
CA
Country
United States
Zip Code
94305
Korner, A F (1996) Reliable individual differences in preterm infants' excitation management. Child Dev 67:1793-805
Sackett, G; Korner, A (1993) Organization of sleep-waking states in conjoined twin neonates. Sleep 16:414-27
Korner, A F; Constantinou, J; Dimiceli, S et al. (1991) Establishing the reliability and developmental validity of a neurobehavioral assessment for preterm infants: a methodological process. Child Dev 62:1200-8
Korner, A F; Lane, N M; Berry, K L et al. (1990) Sleep enhanced and irritability reduced in preterm infants: differential efficacy of three types of waterbeds. J Dev Behav Pediatr 11:240-6
Korner, A F (1990) Infant stimulation. Issues of theory and research. Clin Perinatol 17:173-84
Korner, A F; Brown Jr, B W; Dimiceli, S et al. (1989) Stable individual differences in developmentally changing preterm infants: a replicated study. Child Dev 60:502-13
Korner, A F; Kraemer, H C; Reade, E P et al. (1987) A methodological approach to developing an assessment procedure for testing the neurobehavioral maturity of preterm infants. Child Dev 58:1478-87