The general objective is to advance understanding of brain activity and information processing by studying the relationships between neurophysiological and behavioral measures. Both magnetic field and electrical potential data will be obtained in research on brain activity recording, short-term memory, and linguistic information processing. Based on experimental results in information processing and cognitive psychology, electrophysiological experiments have been designed to correlate Electroencephalogram (EEG) and Magnetoencephalogram (MEG) with cognitive functions and to identify meaningful components of the electrical brain activity. The experiments are organized around electrical recording of brain activity during specific tasks dependent on controlled stimuli. Approaches toward systematic, robust and efficient MEG and EEG measurement and evaluation are emphasized, including Event-Related Potentials and extended applications of the Relative Covariance method that combines simultaneously obtained electrical potential and magnetic field measurements. These techniques have potential significance for clinical assessment as well as experimental studies in memory and linguistic processing. The research has relevance in neuropsychology, neurology, psychology, vision and biopsychology.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Project (R01)
Project #
5R01MH040703-05
Application #
2245027
Study Section
Psychopathology and Clinical Biology Research Review Committee (PCB)
Project Start
1987-04-01
Project End
1994-03-31
Budget Start
1991-05-01
Budget End
1994-03-31
Support Year
5
Fiscal Year
1991
Total Cost
Indirect Cost
Name
University of Rochester
Department
Miscellaneous
Type
Schools of Arts and Sciences
DUNS #
208469486
City
Rochester
State
NY
Country
United States
Zip Code
14627
Chapman, R M; McCrary, J W (1995) EP component identification and measurement by principal components analysis. Brain Cogn 27:288-310
Salustri, C; Chapman, R M; Chapman, J A et al. (1993) Word meaningfulness and event-related potentials during phrase processing. Int J Neurosci 70:117-26
Ricci, G B; Chapman, R M; Erne, S N et al. (1990) Neuromagnetic topography of photoconvulsive response in man. Electroencephalogr Clin Neurophysiol 75:1-12
Salustri, C; Chapman, R M (1989) A simple method for 3-dimensional localization of epileptic activity recorded by simultaneous EEG and MEG. Electroencephalogr Clin Neurophysiol 73:473-8
Garnsey, S M; Tanenhaus, M K; Chapman, R M (1989) Evoked potentials and the study of sentence comprehension. J Psycholinguist Res 18:51-60