Neuropeptide Biosynthesis and Metabolism in the CNS

White, Jeffrey D.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Mental Health (NIMH)
• Type: Research Project (R01)
• Project #: 5R01MH042074-08
• Application #: 2245333
• Study Section: Neurosciences Research Review Committee (BPN)
• Project Start: 1991-09-30
• Project End: 1996-08-31
• Budget Start: 1995-09-30
• Budget End: 1996-08-31
• Support Year: 8
• Fiscal Year: 1995

Institution

• Name: Trophix Pharmaceuticals, Inc.
• City: South Plainfield
• State: NJ
• Country: United States
• Zip Code: 07080

Publications

McCarthy, J B; Walker, M; Pierce, J et al. (1998) Biosynthesis and metabolism of native and oxidized neuropeptide Y in the hippocampal mossy fiber system. J Neurochem 70:1950-63

Yount, G L; Gall, C M; White, J D (1992) Limbic seizures increase cyclophilin mRNA levels in rat hippocampus. Brain Res Mol Brain Res 14:139-42

White, J D; Olchovsky, D; Kershaw, M et al. (1990) Increased hypothalamic content of preproneuropeptide-Y messenger ribonucleic acid in streptozotocin-diabetic rats. Endocrinology 126:765-72

Bruno, J F; Olchovsky, D; White, J D et al. (1990) Influence of food deprivation in the rat on hypothalamic expression of growth hormone-releasing factor and somatostatin. Endocrinology 127:2111-6

Sanacora, G; Kershaw, M; Finkelstein, J A et al. (1990) Increased hypothalamic content of preproneuropeptide Y messenger ribonucleic acid in genetically obese Zucker rats and its regulation by food deprivation. Endocrinology 127:730-7

White, J D; LaGamma, E F (1989) Neuropeptide gene transcription in central and peripheral nervous system tissue by nuclear run-on assay. Methods Enzymol 168:681-90

White, J D; Gall, C M (1987) Differential regulation of neuropeptide and proto-oncogene mRNA content in the hippocampus following recurrent seizures. Brain Res 427:21-9