Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Project (R01)
Project #
5R01MH042545-07
Application #
2245475
Study Section
Special Emphasis Panel (SRCM)
Project Start
1988-02-01
Project End
1998-05-31
Budget Start
1996-09-01
Budget End
1997-05-31
Support Year
7
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Suny Downstate Medical Center
Department
Psychiatry
Type
Schools of Medicine
DUNS #
068552207
City
Brooklyn
State
NY
Country
United States
Zip Code
11203
Rosenblum, Leonard A; Smith, E L P; Altemus, Margaret et al. (2002) Differing concentrations of corticotropin-releasing factor and oxytocin in the cerebrospinal fluid of bonnet and pigtail macaques. Psychoneuroendocrinology 27:651-60
Smith, Eric L P; Batuman, Olcay A; Trost, Ronald C et al. (2002) Transforming growth factor-beta 1 and cortisol in differentially reared primates. Brain Behav Immun 16:140-9
Ludvig, N; Nguyen, M C; Botero, J M et al. (2000) Delivering drugs, via microdialysis, into the environment of extracellularly recorded hippocampal neurons in behaving primates. Brain Res Brain Res Protoc 5:75-84
Coplan, J D; Smith, E L; Trost, R C et al. (2000) Growth hormone response to clonidine in adversely reared young adult primates: relationship to serial cerebrospinal fluid corticotropin-releasing factor concentrations. Psychiatry Res 95:93-102
Coplan, J D; Trost, R C; Owens, M J et al. (1998) Cerebrospinal fluid concentrations of somatostatin and biogenic amines in grown primates reared by mothers exposed to manipulated foraging conditions. Arch Gen Psychiatry 55:473-7
Smith, E L; Coplan, J D; Trost, R C et al. (1997) Neurobiological alterations in adult nonhuman primates exposed to unpredictable early rearing. Relevance to posttraumatic stress disorder. Ann N Y Acad Sci 821:545-8
Trappler, B; Friedman, S (1996) Posttraumatic stress disorder in survivors of the Brooklyn Bridge shooting. Am J Psychiatry 153:705-7
Coplan, J D; Andrews, M W; Rosenblum, L A et al. (1996) Persistent elevations of cerebrospinal fluid concentrations of corticotropin-releasing factor in adult nonhuman primates exposed to early-life stressors: implications for the pathophysiology of mood and anxiety disorders. Proc Natl Acad Sci U S A 93:1619-23
Coplan, J D; Rosenblum, L A; Gorman, J M (1995) Primate models of anxiety. Longitudinal perspectives. Psychiatr Clin North Am 18:727-43
Rosenblum, L A; Coplan, J D; Friedman, S et al. (1994) Adverse early experiences affect noradrenergic and serotonergic functioning in adult primates. Biol Psychiatry 35:221-7

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