The objective of this grant is to continue our longitudinal study of infants and mothers with either high, mid-range, or extremely low levels of depression on maternal and infant outcomes; b) longitudinal observations of naturally occurring maternal and infant interactive behavior are made in the home setting during the first year post partum; c) data on maternal and paternal depressive symptoms, psychiatric co-morbidities, and affective status are collected at each visit; and d) a separate group of mothers with extremely low levels of depressive symptoms is identified and followed. The primary hypotheses to be evaluated are that a) the behavioral and affective styles of mothers with either high or extremely low levels of depressive symptoms will differ from those of mothers with mid-range symptoms; b) patterns of infant behavior and affect will be related to maternal symptom levels; and c) the severity and chronicity of maternal symptoms will have negative effects on mother-infant interaction and infant outcomes. Our hypotheses are guided by the Mutual Regulation Model, which posits that infant development is dependent on the ongoing ability of the infant- caregiver dyad to regulate the infant~s affective states and to foster the infant~s ability to master the major developmental tasks of infancy. The naturally occurring behavior of mothers and infants is videotaped at home when infants are 3,6, and 12 months old. Additionally, infants and mothers are videotaped in the laboratory at 12 months during Ainsworth~s Strange Situation and infant-stranger play. Mothers~ diagnostic history is also obtained. At each age, mothers and fathers complete questionnaires regarding their current depressive symptoms, other psychiatric symptoms, and affective status. Infant and maternal behavior and affect are scored from the videotapes by masked, reliable coders using detailed coding systems. Multivariate techniques will be used to evaluate the hypotheses. Preliminary work and progress on this project has been substantial, and initial results support the hypotheses. This study will markedly increase our understanding of the effects of maternal depressive symptomatology and associated factors on mother-infant interaction and infant socio-emotional development during the first year.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Project (R01)
Project #
2R01MH045547-06A2
Application #
2033777
Study Section
Special Emphasis Panel (ZMH1-BRB-I (02))
Project Start
1990-08-01
Project End
1999-03-31
Budget Start
1997-04-10
Budget End
1998-03-31
Support Year
6
Fiscal Year
1997
Total Cost
Indirect Cost
Name
Children's Hospital Boston
Department
Type
DUNS #
076593722
City
Boston
State
MA
Country
United States
Zip Code
02115
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Tronick, Edward; Reck, Corrina (2009) Infants of depressed mothers. Harv Rev Psychiatry 17:147-56
Beeghly, Marjorie; Weinberg, M Katherine; Olson, Karen L et al. (2002) Stability and change in level of maternal depressive symptomatology during the first postpartum year. J Affect Disord 71:169-80
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Weinberg, M K; Tronick, E Z (1994) Beyond the face: an empirical study of infant affective configurations of facial, vocal, gestural, and regulatory behaviors. Child Dev 65:1503-15