The PI proposes to study the role of cognition, particularly the victim's perception of the meaning of the event, as it relates to an information processing theory of crime-related PTSD. The overall goals of the project are theoretical as well as methodological. The role of cognition and attributions will be examined in a prospective study with recent rape victims to investigate cognition and recovery (Study 1); and within the context of treatment to determine if direct intervention with attributions and beliefs plus exposure is more effective than cognitive therapy only, exposure only, or a minimal attention control (study 2). In Study 1, social support and coping strategies will also be studied as possible mediating factors which may play a role in facilitating or hindering processing the event. Study 1 will compare 200 rape victims at one month and three months postcrime with 100 nonvictims seen at the same intervals. The second study will include 120 rape victims three months or more following their assault, meeting the criteria for PTSD, who will be randomly assigned to one of four conditions: cognitive processing therapy, direct therapeutic exposure, cognitive therapy, or a minimal attention condition. The PI will also attempt to develop multiaxial methods for assessing PTSD in rape victims. A range of techniques will be used to assess concurrent psychophysiological reactions, nonverbal behavior, cognition and emotions, as well as the self-reported symptoms more commonly studied. Furthermore, this study will examine the relationship between these measures in both victim and nonvictim groups. As with the theoretical issues, the methodological issues will be explored as part of the prospective assessment study and the treatment study. During assessments, participants will complete symptom inventories and a diagnostic interview. They will then complete attribution and cognitive scales. The final portion will be a videotaped, physiological assessment. After a resting baseline, subjects will be interviewed about neutral topics, have another baseline phase, then describe the rape, followed by a final baseline.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Project (R01)
Project #
5R01MH046992-03
Application #
3386815
Study Section
Treatment Development and Assessment Research Review Committee (TDA)
Project Start
1991-09-01
Project End
1996-08-31
Budget Start
1993-09-01
Budget End
1994-08-31
Support Year
3
Fiscal Year
1993
Total Cost
Indirect Cost
Name
University of Missouri-St. Louis
Department
Type
Schools of Arts and Sciences
DUNS #
City
Saint Louis
State
MO
Country
United States
Zip Code
63121
Pineles, Suzanne L; Mostoufi, Sheeva M; Ready, C Beth et al. (2011) Trauma reactivity, avoidant coping, and PTSD symptoms: a moderating relationship? J Abnorm Psychol 120:240-6
Feinstein, Brian A; Humphreys, Kathryn L; Bovin, Michelle J et al. (2011) Victim-Offender Relationship Status Moderates the Relationships of Peritraumatic Emotional Responses, Active Resistance, and Posttraumatic Stress Symptomatology in Female Rape Survivors. Psychol Trauma 3:192-200
Kaysen, Debra; Rosen, Gerald; Bowman, Marilyn et al. (2010) Duration of exposure and the dose-response model of PTSD. J Interpers Violence 25:63-74
Gutner, Cassidy A; Pineles, Suzanne L; Griffin, Michael G et al. (2010) Physiological predictors of posttraumatic stress disorder. J Trauma Stress 23:775-84
Chandra, Rachna; Federici, Stephanie; Haskó, György et al. (2010) Female X-chromosome mosaicism for gp91phox expression diversifies leukocyte responses during endotoxemia. Crit Care Med 38:2003-10
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Scher, Christine D; Resick, Patricia A (2005) Hopelessness as a risk factor for post-traumatic stress disorder symptoms among interpersonal violence survivors. Cogn Behav Ther 34:99-107
Kaysen, Debra; Scher, Christine D; Mastnak, Julie et al. (2005) Cognitive mediation of childhood maltreatment and adult depression in recent crime victims. Behav Ther 36:235-44
Kaysen, Debra; Morris, Miranda K; Rizvi, Shireen L et al. (2005) Peritraumatic responses and their relationship to perceptions of threat in female crime victims. Violence Against Women 11:1515-35
Nixon, Reginald D V; Resick, Patricia A; Griffin, Michael G (2004) Panic following trauma: the etiology of acute posttraumatic arousal. J Anxiety Disord 18:193-210

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