The long-term aim of this research is to identify in experimental studies factors that may influence binge eating. The identification of such factors will add to our basic knowledge of the phenomenon of binge eating and may also be useful in developing or refining treatments for binge eating disorder and bulimia nervosa. Analog studies, descriptive studies of bulimia nervosa and binge eating disorder, and treatment studies all suggest that two factors may influence binge eating: dietary restriction and negative mood. Hence, the primary aims of this proposal are to investigate the separate and combined effects of short-term dietary restriction and negative mood on binge eating behavior in the laboratory in a clinical sample. Three studies are proposed. 1. A 2x2 design with patients with binge eating disorder and non-eating-disordered controls allocated to either 1 or 6 hours of food deprivation. 2. A 2x2 design with patients with binge eating disorder and non-eating-disordered controls allocated to either induction of a negative or neutral mood. 3. A 2x2 design with patients with binge eating disorder allocated to one of four groups varying both mood and food deprivation. The data collected will also allow for various descriptive comparisons of eating behavior between binge eaters and non-binge eaters, and binge episodes and non-binge episodes in binge eaters, allowing further understanding of the phenomenology of disordered eating patterns.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Project (R01)
Project #
1R01MH050271-01
Application #
3389465
Study Section
Clinical Psychopathology Review Committee (CPP)
Project Start
1993-01-01
Project End
1995-12-31
Budget Start
1993-01-01
Budget End
1993-12-31
Support Year
1
Fiscal Year
1993
Total Cost
Indirect Cost
Name
Stanford University
Department
Type
Schools of Medicine
DUNS #
800771545
City
Stanford
State
CA
Country
United States
Zip Code
94305
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Kraemer, H C; Stice, E; Kazdin, A et al. (2001) How do risk factors work together? Mediators, moderators, and independent, overlapping, and proxy risk factors. Am J Psychiatry 158:848-56
Stice, E; Agras, W S; Telch, C F et al. (2001) Subtyping binge eating-disordered women along dieting and negative affect dimensions. Int J Eat Disord 30:11-27
Telch, C F; Pratt, E M; Niego, S H (1998) Obese women with binge eating disorder define the term binge. Int J Eat Disord 24:313-7
Telch, C F; Stice, E (1998) Psychiatric comorbidity in women with binge eating disorder: prevalence rates from a non-treatment-seeking sample. J Consult Clin Psychol 66:768-76
le Grange, D; Telch, C F; Agras, W S (1997) Eating and general psychopathology in a sample of Caucasian and ethnic minority subjects. Int J Eat Disord 21:285-93
Telch, C F; Agras, W S (1996) Do emotional states influence binge eating in the obese? Int J Eat Disord 20:271-9
Telch, C F; Agras, W S (1996) The effects of short-term food deprivation on caloric intake in eating-disordered subjects. Appetite 26:221-33