Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Project (R01)
Project #
5R01MH051699-07
Application #
6538706
Study Section
Special Emphasis Panel (ZRG1-SSS-Q (01))
Program Officer
Sieber, Beth-Anne
Project Start
1994-05-01
Project End
2002-12-31
Budget Start
2002-04-01
Budget End
2002-12-31
Support Year
7
Fiscal Year
2002
Total Cost
$304,000
Indirect Cost
Name
University of California San Diego
Department
Pharmacology
Type
Schools of Medicine
DUNS #
077758407
City
La Jolla
State
CA
Country
United States
Zip Code
92093
Sakai, Norihiko; Chun, Jerold; Duffield, Jeremy S et al. (2017) Lysophosphatidic acid signaling through its receptor initiates profibrotic epithelial cell fibroblast communication mediated by epithelial cell derived connective tissue growth factor. Kidney Int 91:628-641
Kihara, Yasuyuki; Groves, Aran; Rivera, Richard R et al. (2015) Dimethyl fumarate inhibits integrin ?4 expression in multiple sclerosis models. Ann Clin Transl Neurol 2:978-83
Sheng, Xiaoyan; Yung, Yun C; Chen, Allison et al. (2015) Lysophosphatidic acid signalling in development. Development 142:1390-5
Kihara, Yasuyuki; Mizuno, Hirotaka; Chun, Jerold (2015) Lysophospholipid receptors in drug discovery. Exp Cell Res 333:171-7
García-Díaz, Beatriz; Riquelme, Raquel; Varela-Nieto, Isabel et al. (2015) Loss of lysophosphatidic acid receptor LPA1 alters oligodendrocyte differentiation and myelination in the mouse cerebral cortex. Brain Struct Funct 220:3701-20
Mirendil, H; Thomas, E A; De Loera, C et al. (2015) LPA signaling initiates schizophrenia-like brain and behavioral changes in a mouse model of prenatal brain hemorrhage. Transl Psychiatry 5:e541
Yung, Yun C; Stoddard, Nicole C; Mirendil, Hope et al. (2015) Lysophosphatidic Acid signaling in the nervous system. Neuron 85:669-82
Chrencik, Jill E; Roth, Christopher B; Terakado, Masahiko et al. (2015) Crystal Structure of Antagonist Bound Human Lysophosphatidic Acid Receptor 1. Cell 161:1633-43
Stoddard, Nicole C; Chun, Jerold (2015) Promising pharmacological directions in the world of lysophosphatidic Acid signaling. Biomol Ther (Seoul) 23:1-11
Herr, Deron R; Lee, Chang-Wook; Wang, Wei et al. (2013) Sphingosine 1-phosphate receptors are essential mediators of eyelid closure during embryonic development. J Biol Chem 288:29882-9

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