Abstract

This is a Shannon Award providing partial support for research projects that fall short of the assigned institute's funding range but are in the margin of excellence. The Shannon award is intended to provide support to test the feasibility of the approach; develop further tests and refine research techniques; perform secondary analysis of available data sets; or conduct discrete projects that can demonstrate the PI's research capabilities or lend additional weight to an already meritorious application. Further scientific data for the CRISP System are unavailable at this time.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Project (R01)
Project #
5R01MH052841-04
Application #
2416068
Study Section
Epidemiology and Genetics Review Committee (EPI)
Project Start
1994-09-30
Project End
2000-04-30
Budget Start
1997-06-01
Budget End
1998-04-30
Support Year
4
Fiscal Year
1997
Total Cost
Indirect Cost

  Institution

Name
University of Iowa
Department
Public Health & Prev Medicine
Type
Schools of Medicine
DUNS #
041294109
City
Iowa City
State
IA
Country
United States
Zip Code
52242

  Publications

Wassink, Thomas H; Vieland, Veronica J; Sheffield, Val C et al. (2008) Posterior probability of linkage analysis of autism dataset identifies linkage to chromosome 16. Psychiatr Genet 18:85-91
Wassink, Thomas H; Losh, Molly; Frantz, Rebecca S et al. (2005) A case of autism and uniparental disomy of chromosome 1. Hum Genet 117:200-6
Bartlett, Christopher W; Vieland, Veronica J (2005) Two novel quantitative trait linkage analysis statistics based on the posterior probability of linkage: application to the COGA families. BMC Genet 6 Suppl 1:S121
George, Andrew W; Mangin, LaVonne A; Bartlett, Christopher W et al. (2005) Calculation of multipoint likelihoods using flanking marker data: a simulation study. BMC Genet 6 Suppl 1:S44
Bartlett, Christopher W; Goedken, Rhinda; Vieland, Veronica J (2005) Effects of updating linkage evidence across subsets of data: reanalysis of the autism genetic resource exchange data set. Am J Hum Genet 76:688-95
Vieland, Veronica J; Huang, Jian (2003) Two-locus heterogeneity cannot be distinguished from two-locus epistasis on the basis of affected-sib-pair data. Am J Hum Genet 73:223-32
Collaborative Linkage Study of Autism (2001) An autosomal genomic screen for autism. Am J Med Genet 105:609-15
Vieland, V J; Wang, K; Huang, J (2001) Power to detect linkage based on multiple sets of data in the presence of locus heterogeneity: comparative evaluation of model-based linkage methods for affected sib pair data. Hum Hered 51:199-208
Wassink, T H; Piven, J; Patil, S R (2001) Chromosomal abnormalities in a clinic sample of individuals with autistic disorder. Psychiatr Genet 11:57-63
Wang, K; Huang, J; Vieland, V J (2000) The consistency of the posterior probability of linkage. Ann Hum Genet 64:533-53