This application seeks to test the effects of behavioral interventions on quality of life, psychosocial, and health status indices in a randomized controlled trail with 432 ethnically representative female AIDS patients. These patients will be recruited from the three largest AIDS epicenters for women: Miami, Florida; Newark, New Jersey; and Bronx, New York. The sample will include African-American, Caribbean, and Hispanic women who have recently (within the past 6 months) been diagnosed with case-defined AIDS. The 10-week cognitive behavioral stress management (CBSM) intervention to be used in the proposed study has been/is being tested by investigators on this research team in several studies with HIV+ women and gay men, with encouraging findings. This application will test the effects of CBSM with African-American, Caribbean, Hispanic, and Caucasian women at a more advanced stage in the HIV/AIDS disease process and will incorporate additional therapeutic strategies found to be effective by other investigators with patients confronting life threatening diseases. This expanded intervention will focus upon enhancing personal control over life stressors, expanding the repertoire of effective coping strategies, and increasing emotional expression and social support to reduce the deleterious affective and behavioral sequelae of AIDS. The objective of this study will be to determine (a) how effective the proposed expanded intervention will be for women who have already progressed to case-defined AIDS at the time of intervention; (b) whether active efforts to help women maintain their intervention-acquired skills will predict improved psychological, behavioral, and symptom status at follow-up; and (c) whether these effects generalize across ethnic boundaries. Thus, the proposed study will test the capacity of the expanded intervention to enhance problem solving coping strategies and perceptions of social support and to reduce the inappropriate use of denial and disengagement with concomitant improvement in quality of life indices and reduction in signs and symptoms associated with disease progression.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Project (R01)
Project #
5R01MH055463-04
Application #
2890773
Study Section
Psychobiological, Biological, and Neurosciences Subcommittee (MHAI)
Program Officer
Pequegnat, Willo
Project Start
1996-09-30
Project End
2000-08-31
Budget Start
1999-05-01
Budget End
2000-08-31
Support Year
4
Fiscal Year
1999
Total Cost
Indirect Cost
Name
University of Miami School of Medicine
Department
Psychiatry
Type
Schools of Medicine
DUNS #
City
Miami
State
FL
Country
United States
Zip Code
33146
Weiss, Stephen M; Tobin, Jonathan N; Lopez, Maria et al. (2015) Translating an Evidence-Based Behavioral Intervention for Women Living with HIV into Clinical Practice: The SMART/EST Women's Program. Int J Behav Med 22:415-24
Jones, Deborah; Owens, Mary; Kumar, Mahendra et al. (2014) The effect of relaxation interventions on cortisol levels in HIV-seropositive women. J Int Assoc Provid AIDS Care 13:318-23
Jones, Deborah; Owens, Mary; Kumar, Mahendra et al. (2014) The effect of relaxation interventions on cortisol levels in HIV-seropositive women. J Int Assoc Provid AIDS Care 13:318-23
Jones, Deborah L; Lopez, Maria; Simons, Hannah et al. (2013) Translation of a comprehensive health behavior intervention for women living with HIV: the SMART/EST Women's Program. Transl Behav Med 3:416-25
Weiss, Stephen M; Jones, Deborah L; Lopez, Maria et al. (2011) The many faces of translational research: a tale of two studies. Transl Behav Med 1:327-330
Jones, Deborah L; Ishii Owens, Mary; Lydston, David et al. (2010) Self-efficacy and distress in women with AIDS: the SMART/EST women's project. AIDS Care 22:1499-508
Jones, Deborah L; McPherson-Baker, Shvawn; Lydston, David et al. (2007) Efficacy of a group medication adherence intervention among HIV positive women: the SMART/EST Women's Project. AIDS Behav 11:79-86
Lopez, Eliot; Jones, Deborah L; Ishii, Mary et al. (2007) HIV Medication Adherence and Substance Use: The Smartest Women's Project. Am J Infect Dis 3:240-247
Segal-Isaacson, C J; Tobin, Jonathan N; Weiss, Stephen M et al. (2006) Improving dietary habits in disadvantaged women with HIV/AIDS: the SMART/EST women's project. AIDS Behav 10:659-70
Laperriere, Arthur; Ironson, Gail H; Antoni, Michael H et al. (2005) Decreased depression up to one year following CBSM+ intervention in depressed women with AIDS: the smart/EST women's project. J Health Psychol 10:223-31

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