Eating disorders involving recurrent binge eating (binge eating disorders) pose a significant risk to the health and psychological adjustment of young women. Current knowledge of binge eating disorders is limited by a) the virtual exclusion of minority women from study samples; b) the paucity of studies of women with spectrum binge eating disorders; and c) the over reliance in risk factor studies on retrospective assessment of exposure to risk.
As Aim I, the proposed study will assess a cohort of 2,379 young adult black and white women to describe the spectrum of binge eating disorders. Using state-of-the-art case finding interview methods, we will determine prevalence of bulimia nervosa (BN), binge eating disorder (BED), and their spectrum variants (defined as meeting all but one of the criteria required for full syndrome diagnosis); we will also identify presence of current Axis I psychiatric disorders. To determine clinical significance of BN, BED, and their spectrum variants in this community-based sample, we will compare women with a binge eating disorder and healthy controls on measures of obesity and psychological adjustment. The association of race and concomitant variables with eating disorder cases and controls will be examined.
Aim II of the study is to develop an empirically based, multifactorial model of risk for binge eating disorders that considers three major risk domains: familial context, constitutional vulnerability, and personal vulnerability. For assessment of exposure to risk, data will be utilized that have been collected prospectively and longitudinally over a period of ten years in this exceptionally well-maintained cohort. We will examine race differences in the relative contribution of risk factors to the development of binge eating disorders; determine specificity of risk; and compare exposure to risk in women with full syndrome versus women with spectrum binge eating disorders. Our study should generate information relevant for primary prevention by identifying high risk groups and risk factors that may be amenable to change.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Project (R01)
Project #
5R01MH057897-03
Application #
6165213
Study Section
Health Behavior and Prevention Review Committee (HBPR)
Program Officer
Bourdon, Karen H
Project Start
1998-05-01
Project End
2003-02-28
Budget Start
2000-03-01
Budget End
2003-02-28
Support Year
3
Fiscal Year
2000
Total Cost
$487,011
Indirect Cost
Name
Wesleyan University
Department
Psychology
Type
Schools of Arts and Sciences
DUNS #
City
Middletown
State
CT
Country
United States
Zip Code
06459
Gunderson, Erica P; Schreiber, George; Striegel-Moore, Ruth et al. (2012) Pregnancy during adolescence has lasting adverse effects on blood lipids: a 10-year longitudinal study of black and white females. J Clin Lipidol 6:139-49
Thompson, Douglas R; Obarzanek, Eva; Franko, Debra L et al. (2007) Childhood overweight and cardiovascular disease risk factors: the National Heart, Lung, and Blood Institute Growth and Health Study. J Pediatr 150:18-25
Striegel-Moore, Ruth H; Dohm, Faith-Anne; Kraemer, Helena C et al. (2007) Risk factors for binge-eating disorders: an exploratory study. Int J Eat Disord 40:481-7
Biro, Frank M; Striegel-Moore, Ruth H; Franko, Debra L et al. (2006) Self-esteem in adolescent females. J Adolesc Health 39:501-7
Striegel-Moore, Ruth H; Franko, Debra L; Thompson, Douglas et al. (2006) Caffeine intake in eating disorders. Int J Eat Disord 39:162-5
Franko, Debra L; Thompson, Douglas; Barton, Bruce A et al. (2005) Prevalence and comorbidity of major depressive disorder in young black and white women. J Psychiatr Res 39:275-83
Striegel-Moore, Ruth H; Dohm, Faith-Anne; Hook, Julie M et al. (2005) Night eating syndrome in young adult women: prevalence and correlates. Int J Eat Disord 37:200-6
Franko, Debra L; Striegel-Moore, Ruth H; Thompson, Douglas et al. (2005) Does adolescent depression predict obesity in black and white young adult women? Psychol Med 35:1505-13
Franko, Debra L; Striegel-Moore, Ruth H; Bean, Judy et al. (2005) Self-reported symptoms of depression in late adolescence to early adulthood: a comparison of African-American and Caucasian females. J Adolesc Health 37:526-9
Striegel-Moore, Ruth H; Dohm, Faith-Anne; Kraemer, Helena C et al. (2005) Health services use in women with a history of bulimia nervosa or binge eating disorder. Int J Eat Disord 37:11-8

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