Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Project (R01)
Project #
5R01MH063114-02
Application #
6685323
Study Section
Special Emphasis Panel (ZRG1-BBBP-1 (01))
Program Officer
Winsky, Lois M
Project Start
2002-12-01
Project End
2004-08-31
Budget Start
2003-12-01
Budget End
2004-08-31
Support Year
2
Fiscal Year
2004
Total Cost
$200,999
Indirect Cost
Name
Ohio State University
Department
Neurosciences
Type
Schools of Medicine
DUNS #
832127323
City
Columbus
State
OH
Country
United States
Zip Code
43210
Sarter, Martin; Martinez, Vicente; Kozak, Rouba (2009) A neurocognitive animal model dissociating between acute illness and remission periods of schizophrenia. Psychopharmacology (Berl) 202:237-58
Martinez, Vicente; Sarter, Martin (2008) Detection of the moderately beneficial cognitive effects of low-dose treatment with haloperidol or clozapine in an animal model of the attentional impairments of schizophrenia. Neuropsychopharmacology 33:2635-47
Kozak, Rouba; Martinez, Vicente; Young, Damon et al. (2007) Toward a neuro-cognitive animal model of the cognitive symptoms of schizophrenia: disruption of cortical cholinergic neurotransmission following repeated amphetamine exposure in attentional task-performing, but not non-performing, rats. Neuropsychopharmacology 32:2074-86
Briand, Lisa A; Gritton, Howard; Howe, William M et al. (2007) Modulators in concert for cognition: modulator interactions in the prefrontal cortex. Prog Neurobiol 83:69-91
Brooks, Julie M; Sarter, Martin; Bruno, John P (2007) D2-like receptors in nucleus accumbens negatively modulate acetylcholine release in prefrontal cortex. Neuropharmacology 53:455-63
Sarter, Martin; Bruno, John P; Parikh, Vinay (2007) Abnormal neurotransmitter release underlying behavioral and cognitive disorders: toward concepts of dynamic and function-specific dysregulation. Neuropsychopharmacology 32:1452-61
Sarter, Martin (2007) Cholinergic control of attention to cues guiding established performance versus learning: theoretical comment on Maddux, Kerfoot, Chatterjee, and Holland (2007). Behav Neurosci 121:233-5
Zmarowski, Amy; Sarter, Martin; Bruno, John P (2007) Glutamate receptors in nucleus accumbens mediate regionally selective increases in cortical acetylcholine release. Synapse 61:115-23
Sarter, Martin (2006) Preclinical research into cognition enhancers. Trends Pharmacol Sci 27:602-8
Parikh, V; Apparsundaram, S; Kozak, R et al. (2006) Reduced expression and capacity of the striatal high-affinity choline transporter in hyperdopaminergic mice. Neuroscience 141:379-89

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