The overall aim of the current proposal is to develop knowledge about the prevention of panic disorder (PD) using a specialized anxiety-smoking cessation intervention. This program will target, within the context of a controlled randomized selected prevention program, two malleable vulnerability factors for the development of PD - anxiety sensitivity (the fear of anxiety and anxiety-related sensations) and cigarette smoking. Panic disorder is a common, severe, and chronic condition characterized by recurrent panic attacks and worry about the possibility of experiencing a future panic attack [American Psychiatric Association (APA), 1994]. Cigarette smoking, the leading cause of death and disability in North America [Centers for Disease Control and Prevention (CDC), 1994], is particularly common among those with, or at risk for, developing PD; approximately 40% of individuals with PD are currently regular smokers and over 60% have a lifetime history of smoking (Amering et al., 1999; Lasser et al., 2000). There is empirical evidence that suggests bi-directional associations between smoking and panic factors, consistent with a positive feedback loop process, resulting in a variety of negative effects. This issue sits on the backdrop of me larger recognition that, although substance use problems frequently co-occur with panic and other forms of psychopathology, there has been little effort to develop theoretically-integrated programs to target behavioral processes that contribute to this comorbidity (Otto, Powers, & Fischmann, in press; Zvolensky & Schmidt, 2004). The present proposal aims to begin to fill this gap in the existing literature by prospectively evaluating quitting behavior and panic outcomes within the context of a controlled randomized selected prevention program. The prevention program, implemented across two sites, will utilize cognitive restructuring and interoceptive exposure strategies with a specific focus on reducing the fear of anxiety and related anxiety processes in order to (1) decrease the development of panic attacks and panic disorder; and (2) facilitate successful cessation. This Panic-Smoking Prevention Program (PSPP) will integrate interoceptive exposure, cognitive restructuring, and psychoeducation exercises developed for panic prevention and treatment programs with standard smoking cessation counseling. The PSPP program will be compared to a standard anxiety sensitivity amelioration intervention, standard smoking cessation, and a health information control condition. ? ?

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Project (R01)
Project #
3R01MH076629-01A2S1
Application #
7541070
Study Section
Adult Psychopathology and Disorders of Aging Study Section (APDA)
Program Officer
Muehrer, Peter R
Project Start
2007-12-01
Project End
2010-03-31
Budget Start
2007-12-01
Budget End
2008-03-31
Support Year
1
Fiscal Year
2008
Total Cost
$18,623
Indirect Cost
Name
University of Vermont & St Agric College
Department
Psychology
Type
Schools of Arts and Sciences
DUNS #
066811191
City
Burlington
State
VT
Country
United States
Zip Code
05405
Garey, Lorra; Kauffman, Brooke Y; Manning, Kara F et al. (2018) The Effect of Positive and Negative Affect on Early Treatment Milestones in the Context of Integrated Smoking Treatment. J Addict Med :
Bakhshaie, Jafar; Kulesz, Paulina A; Garey, Lorra et al. (2018) A prospective investigation of the synergistic effect of change in anxiety sensitivity and dysphoria on tobacco withdrawal. J Consult Clin Psychol 86:69-80
Guillot, Casey R; Blumenthal, Heidemarie; Zvolensky, Michael J et al. (2018) Anxiety sensitivity components in relation to alcohol and cannabis use, motives, and problems in treatment-seeking cigarette smokers. Addict Behav 82:166-173
Kauffman, Brooke Y; Garey, Lorra; Jardin, Charles et al. (2018) Body Mass Index and functional impairment: the explanatory role of anxiety sensitivity among treatment-seeking smokers. Psychol Health Med 23:232-243
Rogers, Andrew H; Bakhshaie, Jafar; Garey, Lorra et al. (2018) Individual differences in emotion dysregulation and trajectory of withdrawal symptoms during a quit attempt among treatment-seeking smokers. Behav Res Ther :
Zvolensky, Michael J; Garey, Lorra; Fergus, Thomas A et al. (2018) Refinement of anxiety sensitivity measurement: The Short Scale Anxiety Sensitivity Index (SSASI). Psychiatry Res 269:549-557
Garey, Lorra; Peraza, Natalia; Smit, Tanya et al. (2018) Sex differences in smoking constructs and abstinence: The explanatory role of smoking outcome expectancies. Psychol Addict Behav 32:660-669
Albanese, Brian J; Macatee, Richard J; Boffa, Joseph W et al. (2018) Interactive effects of traumatic brain injury and anxiety sensitivity on PTSD symptoms: A replication and extension in two clinical samples. Cognit Ther Res 42:510-523
Zvolensky, Michael J; Garey, Lorra; Allan, Nicolas P et al. (2018) Effects of anxiety sensitivity reduction on smoking abstinence: An analysis from a panic prevention program. J Consult Clin Psychol 86:474-485
Garey, Lorra; Manning, Kara; Jardin, Charles et al. (2018) Smoking Consequences Questionnaire: A reevaluation of the psychometric properties across two independent samples of smokers. Psychol Assess 30:678-692

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