Depression and anxiety are highly comorbid, and this comorbidity is a negative prognostic indicator of treatment outcomes with antidepressant medication. However, research conflicts on the effects of comorbid anxiety on outcomes with cognitive-behavioral therapy (CBT) for depression. The role of comorbid anxiety in treating a subtype of depression, winter seasonal affective disorder (SAD), has yet to be studied. The current project proposes to examine anxiety as both an outcome and a moderator of treatment outcomes in a parent trial comparing light therapy and CBT tailored to SAD (CBT-SAD).
Aim 1 will examine anxiety as an outcome after acute treatment and at a follow-up one winter later.
Aims 2 and 3 will examine baseline anxiety?both dimensional and syndromal anxiety, respectively?as a predictor of SAD treatment outcomes at post-treatment and at a follow-up one winter later. Anxiety disorders will be assessed using the Structured Clinical Interview for DSM-5 (SCID-5) at intake. Anxiety will be dimensionally assessed using the Beck Anxiety Inventory (BAI) at pre-, mid-, and post- treatment, as well as at the one winter follow-up.

Public Health Relevance

Depression comorbid with anxiety is common and associated with worse treatment outcomes. The role of comorbid anxiety in treating a subtype of depression, winter seasonal affective disorder (SAD), has yet to be examined. Using a parent clinical trial comparing the efficacy of light therapy and cognitive-behavioral therapy for SAD, this diversity supplement proposes to examine (1) anxiety as a treatment outcome and (2) the effects of baseline anxiety symptom severity and anxiety disorder diagnostic status on treatment outcomes.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Project (R01)
Project #
3R01MH112819-02S2
Application #
10029783
Study Section
Program Officer
Rudorfer, Matthew V
Project Start
2018-05-01
Project End
2023-02-28
Budget Start
2020-02-01
Budget End
2020-02-29
Support Year
2
Fiscal Year
2020
Total Cost
Indirect Cost
Name
University of Vermont & St Agric College
Department
Psychology
Type
Schools of Arts and Sciences
DUNS #
066811191
City
Burlington
State
VT
Country
United States
Zip Code
05405