Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS017131-14
Application #
2263158
Study Section
Neurology B Subcommittee 2 (NEUB)
Project Start
1994-09-01
Project End
1998-08-30
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
14
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Cincinnati
Department
Neurosurgery
Type
Schools of Medicine
DUNS #
City
Cincinnati
State
OH
Country
United States
Zip Code
45221
Kudwa, A E; Shoemaker, S E; Crutcher, K A et al. (2002) Evidence for reduced accumulation of exogenous neurotrophin by aged sympathetic neurons. Brain Res 948:24-32
Pettigrew, D B; Levin, L; Crutcher, K A (2000) Sympathetic neurite growth on central nervous system sections is region-specific and unaltered by aging. Neurobiol Aging 21:629-38
Shafer, A J; Crutcher, K A; Isaacson, L G (2000) Remodeling of adult sensory axons in the superior cervical ganglion in response to exogenous nerve growth factor. Brain Res 864:252-62
Walsh, G S; Krol, K M; Kawaja, M D (1999) Absence of the p75 neurotrophin receptor alters the pattern of sympathosensory sprouting in the trigeminal ganglia of mice overexpressing nerve growth factor. J Neurosci 19:258-73
Kuchel, G A; Crutcher, K A; Naheed, U et al. (1999) NGF expression in the aged rat pineal gland does not correlate with loss of sympathetic axonal branches and varicosities. Neurobiol Aging 20:685-93
Walsh, G S; Krol, K M; Crutcher, K A et al. (1999) Enhanced neurotrophin-induced axon growth in myelinated portions of the CNS in mice lacking the p75 neurotrophin receptor. J Neurosci 19:4155-68
Isaacson, L G; Crutcher, K A (1998) Uninjured aged sympathetic neurons sprout in response to exogenous NGF in vivo. Neurobiol Aging 19:333-9
Isaacson, L G; Mareska, M; Nixdorf, W et al. (1997) Dose-dependent response of mature cerebrovascular axons in vivo following intracranial infusion of nerve growth factor. Neurosci Lett 222:21-4
Kawaja, M D; Crutcher, K A (1997) Sympathetic axons invade the brains of mice overexpressing nerve growth factor. J Comp Neurol 383:60-72
Isaacson, L G; Billieu, S C (1996) Increased perivascular norepinephrine following intracerebroventricular infusion of NGF into adult rats. Exp Neurol 139:54-60

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