The proposed research addresses several crucial aspects of Parkinsonian motor behavior by breaking down motor programming processes into identifiable functional operations. By systematically varying the functional aspects of voluntary movement preparation more will be understood about the information processing deficits that result from structure disturbances and set the stage for more detailed accounts of the motor physiology involved. The research is directed toward identifying, isolating, and documenting which motor processes contribute to akinetic and bradykinetic disorders through established behavior methods commonly employed in the study of motor control of normals. Five experiments are proposed which probe the following movement organization processes: Response Determination, Response Specification, Preprogramming and Reprogramming, and Bimanual Control. We are confident that both the scientist and the clinician will be served by the data: the former by having information on the locus of the disorders and the latter by being presented with interpretations from which more objective rehabilitory procedures can enolve.

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS017421-02
Application #
3397562
Study Section
Neurology B Subcommittee 1 (NEUB)
Project Start
1984-07-01
Project End
1987-06-30
Budget Start
1985-07-01
Budget End
1986-06-30
Support Year
2
Fiscal Year
1985
Total Cost
Indirect Cost
Name
University of Wisconsin Madison
Department
Type
Schools of Education
DUNS #
161202122
City
Madison
State
WI
Country
United States
Zip Code
53715
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Rand, M K; Stelmach, G E; Bloedel, J R (2000) Movement accuracy constraints in Parkinson's disease patients. Neuropsychologia 38:203-12
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Seidler-Dobrin, R D; He, J; Stelmach, G E (1998) Coactivation to reduce variability in the elderly. Motor Control 2:314-30
Saling, M; Alberts, J; Stelmach, G E et al. (1998) Reach-to-grasp movements during obstacle avoidance. Exp Brain Res 118:251-8
Wang, J; Stelmach, G E (1998) Coordination among the body segments during reach-to-grasp action involving the trunk. Exp Brain Res 123:346-50
Seidler-Dobrin, R D; Stelmach, G E (1998) Persistence in visual feedback control by the elderly. Exp Brain Res 119:467-74
Rand, M K; Alberts, J L; Stelmach, G E et al. (1997) The influence of movement segment difficulty on movements with two-stroke sequence. Exp Brain Res 115:137-46

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