Spasmodic Dysphnia (SD) is a poorly understood, highly controversial voice disorder whose effects are frequently devastating to the lives of its victims. While a number of treatments have been reported to produce some degree of improvements in some patients, for most it remains an intractable, irreversible, profoundly handicapping disability. The question of which patients can be helped by a particular treatment modality remains unresolved. Hypothesized etiologies include (1) psychogenic, (2) neurologic, (3) both psychogenic and neurologic, with no established means of differential diagnosis. Proposed sites of lesion in neurologic theory include peripheral nerve, basal ganglia, brain stem, and cortex. Proposed herein is a systematic investigation of 30 SD patients with respect to (1) objective evaluations of selected neurological functions including visual, auditory, and vagal-visceral, (2) reported and diagnosed non-phonatory symptoms, including course of the disorder and response to treatment(s), and (3) patterns of respiratory, phonatory, and articulatory dysfunction. Inferential and correlational analyses of the results of these studies will yield insight into etiology, probable site(s) of lesion(s), and differential diagnosis.

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS018276-03
Application #
3398317
Study Section
Communication Sciences and Disorders (CMS)
Project Start
1983-01-01
Project End
1986-08-31
Budget Start
1985-01-01
Budget End
1986-08-31
Support Year
3
Fiscal Year
1985
Total Cost
Indirect Cost
Name
University of Texas-Dallas
Department
Type
Other Specialized Schools
DUNS #
City
Richardson
State
TX
Country
United States
Zip Code
75080
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