Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS021151-10
Application #
2264087
Study Section
Physiology Study Section (PHY)
Program Officer
Baughman, Robert W
Project Start
1984-07-01
Project End
1997-06-30
Budget Start
1995-07-01
Budget End
1997-06-30
Support Year
10
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of Hawaii
Department
Biology
Type
Organized Research Units
DUNS #
121911077
City
Honolulu
State
HI
Country
United States
Zip Code
96822
Gessner, Guido; Macianskiene, Regina; Starkus, John G et al. (2010) The amiodarone derivative KB130015 activates hERG1 potassium channels via a novel mechanism. Eur J Pharmacol 632:52-9
Starkus, John G; Varga, Zoltan; Schonherr, Roland et al. (2003) Mechanisms of the inhibition of Shaker potassium channels by protons. Pflugers Arch 447:44-54
Varga, Zoltan; Rayner, Martin D; Starkus, John G (2002) Cations affect the rate of gating charge recovery in wild-type and W434F Shaker channels through a variety of mechanisms. J Gen Physiol 119:467-85
Starkus, J G; Heinemann, S H; Rayner, M D (2000) Voltage dependence of slow inactivation in Shaker potassium channels results from changes in relative K(+) and Na(+) permeabilities. J Gen Physiol 115:107-22
Bao, H; Hakeem, A; Henteleff, M et al. (1999) Voltage-insensitive gating after charge-neutralizing mutations in the S4 segment of Shaker channels. J Gen Physiol 113:139-51
Starkus, J G; Kuschel, L; Rayner, M D et al. (1998) Macroscopic Na+ currents in the ""Nonconducting"" Shaker potassium channel mutant W434F. J Gen Physiol 112:85-93
Starkus, J G; Kuschel, L; Rayner, M D et al. (1997) Ion conduction through C-type inactivated Shaker channels. J Gen Physiol 110:539-50
Ruben, P C; Fleig, A; Featherstone, D et al. (1997) Effects of clamp rise-time on rat brain IIA sodium channels in Xenopus oocytes. J Neurosci Methods 73:113-22
Starkus, J G; Schlief, T; Rayner, M D et al. (1995) Unilateral exposure of Shaker B potassium channels to hyperosmolar solutions. Biophys J 69:860-72
Fleig, A; Ruben, P C; Rayner, M D (1994) Kinetic mode switch of rat brain IIA Na channels in Xenopus oocytes excised macropatches. Pflugers Arch 427:399-405

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