Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS021460-10
Application #
2264187
Study Section
Neurology B Subcommittee 2 (NEUB)
Project Start
1986-07-01
Project End
1997-06-30
Budget Start
1995-07-01
Budget End
1997-06-30
Support Year
10
Fiscal Year
1995
Total Cost
Indirect Cost

  Institution

Name
College of William and Mary
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
074762238
City
Williamsburg
State
VA
Country
United States
Zip Code
23187

  Publications

Zhang, Z; Krebs, C J; Guth, L (1997) Experimental analysis of progressive necrosis after spinal cord trauma in the rat: etiological role of the inflammatory response. Exp Neurol 143:141-52
Zhang, Z; Guth, L (1997) Experimental spinal cord injury: Wallerian degeneration in the dorsal column is followed by revascularization, glial proliferation, and nerve regeneration. Exp Neurol 147:159-71
Fujiki, M; Zhang, Z; Guth, L et al. (1996) Genetic influences on cellular reactions to spinal cord injury: activation of macrophages/microglia and astrocytes is delayed in mice carrying a mutation (WldS) that causes delayed Wallerian degeneration. J Comp Neurol 371:469-84
Zhang, Z; Fujiki, M; Guth, L et al. (1996) Genetic influences on cellular reactions to spinal cord injury: a wound-healing response present in normal mice is impaired in mice carrying a mutation (WldS) that causes delayed Wallerian degeneration. J Comp Neurol 371:485-95
Guth, L; Zhang, Z; Roberts, E (1994) Key role for pregnenolone in combination therapy that promotes recovery after spinal cord injury. Proc Natl Acad Sci U S A 91:12308-12
Guth, L; Zhang, Z; DiProspero, N A et al. (1994) Spinal cord injury in the rat: treatment with bacterial lipopolysaccharide and indomethacin enhances cellular repair and locomotor function. Exp Neurol 126:76-87
Guth, L; Albers, R W; Barrett, C P et al. (1988) Quantitative evaluation of axonal regeneration by immunochemical assay for neurofilament protein. Exp Neurol 100:83-97