Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
3R01NS022448-02S1
Application #
3404833
Study Section
Neurology C Study Section (NEUC)
Project Start
1986-08-01
Project End
1988-06-30
Budget Start
1986-08-01
Budget End
1987-06-30
Support Year
2
Fiscal Year
1986
Total Cost
Indirect Cost
Name
University of Texas Health Science Center Houston
Department
Type
Schools of Medicine
DUNS #
City
Houston
State
TX
Country
United States
Zip Code
77225
Kussie, P H; Albright, G; Linthicum, D S (1989) Production and characterization of monoclonal idiotypes and anti-idiotypes for small ligands. Methods Enzymol 178:49-63
Kussie, P H; Sherman, M A; Marchetti, D et al. (1989) Molecular analysis of monoclonal idiotypes and anti-idiotypes. Methods Enzymol 178:91-107
Linthicum, D S; Bolger, M B; Kussie, P H et al. (1988) Analysis of idiotypic and anti-idiotypic antibodies as models of receptor and ligand. Clin Chem 34:1676-80
Sherman, M A; Deans, R J; Bolger, M B (1988) Haloperidol binding to monoclonal antibodies. Hypervariable region amino acid sequence determination. J Biol Chem 263:4059-63
Sherman, M A; Bolger, M B (1988) Haloperidol binding to monoclonal antibodies. Predictions of three-dimensional combining site structure via computer modeling. J Biol Chem 263:4064-74
Hall, E R; Lane, C L; Linthicum, D S (1987) Monoclonal antibody against TXB2: its use in solid and liquid phase radioimmunoassays. Prostaglandins Leukot Med 30:103-9
Sherman, M A; Linthicum, D S; Bolger, M B (1986) Haloperidol binding to monoclonal antibodies: conformational analysis and relationships to D-2 receptor binding. Mol Pharmacol 29:589-98
Simmons, R D; Linthicum, D S (1986) A simple 'free 3H-ligand' assay for rapid screening of hybridoma monoclonal antibodies against neurotransmitter analogs and anti-idiotype antibodies. J Neuroimmunol 11:245-9
Linthicum, D S; Bolger, M B (1985) Using molecular mimicry to produce anti-receptor antibodies. Bioessays 3:213-7