Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS023744-02
Application #
3407570
Study Section
Physiological Chemistry Study Section (PC)
Project Start
1986-12-01
Project End
1988-04-30
Budget Start
1988-01-01
Budget End
1988-04-30
Support Year
2
Fiscal Year
1988
Total Cost
Indirect Cost
Name
University of Tennessee Health Science Center
Department
Type
Schools of Medicine
DUNS #
941884009
City
Memphis
State
TN
Country
United States
Zip Code
38163
Venkataraman, V; Duda, T; Sharma, R K (1999) alpha2D/A-adrenergic receptor gene induction in the retina by phorbol ester: involvement of an AP-2 element. Genes Cells 4:161-73
Duda, T; Venkataraman, V; Goraczniak, R et al. (1999) Functional consequences of a rod outer segment membrane guanylate cyclase (ROS-GC1) gene mutation linked with Leber's congenital amaurosis. Biochemistry 38:509-15
Duda, T; Venkataraman, V; Krishnan, A et al. (1998) Rod outer segment membrane guanylate cyclase type 1 (ROS-GC1) gene: structure, organization and regulation by phorbol ester, a protein kinase C activator. Mol Cell Biochem 189:63-70
Duda, T; Goraczniak, R M; Pozdnyakov, N et al. (1998) Differential activation of rod outer segment membrane guanylate cyclases, ROS-GC1 and ROS-GC2, by CD-GCAP and identification of the signaling domain. Biochem Biophys Res Commun 242:118-22
Krishnan, A; Goraczniak, R M; Duda, T et al. (1998) Third calcium-modulated rod outer segment membrane guanylate cyclase transduction mechanism. Mol Cell Biochem 178:251-9
Venkataraman, V; Duda, T; Sharma, R K (1998) The alpha(2D/A)-adrenergic receptor-linked membrane guanylate cyclase: a new signal transduction system in the pineal gland. FEBS Lett 427:69-73
Sharma, R K; Duda, T (1997) Plasma membrane guanylate cyclase. A multimodule transduction system. Adv Exp Med Biol 407:271-9
Venkataraman, V; Duda, T; Sharma, R K (1997) A role for amino acid residues in the third cytoplasmic loop in defining the ligand binding characteristics of the alpha2D-adrenergic receptor. Mol Cell Biochem 177:125-9
Venkataraman, V; Duda, T; Sharma, R K (1997) The bovine alpha 2D-adrenergic receptor gene: structure, expression in retina, and pharmacological characterization of the encoded receptor. Mol Cell Biochem 177:113-23
Goraczniak, R; Duda, T; Sharma, R K (1997) Structural and functional characterization of a second subfamily member of the calcium-modulated bovine rod outer segment membrane guanylate cyclase, ROS-GC2. Biochem Biophys Res Commun 234:666-70

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