Neurofibrous Proteins in Normal and Aging Brain

Gaskin, Felicia

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Neurological Disorders and Stroke (NINDS)
• Type: Research Project (R01)
• Project #: 7R01NS024489-04
• Application #: 3409169
• Study Section: Neurology A Study Section (NEUA)
• Project Start: 1988-12-01
• Project End: 1990-11-30
• Budget Start: 1988-12-01
• Budget End: 1990-11-30
• Support Year: 4
• Fiscal Year: 1988

Institution

• Name: University of Virginia
• Type: Schools of Medicine
• DUNS #: 001910777
• City: Charlottesville
• State: VA
• Country: United States
• Zip Code: 22904

Publications

Xu, S; Gaskin, F (1998) Probing the ATP binding site of tubulin with thiotriphosphate analogues of ATP. Biochim Biophys Acta 1383:111-22

Faris, M; Gaskin, F; Parsons, J T et al. (1994) CD40 signaling pathway: anti-CD40 monoclonal antibody induces rapid dephosphorylation and phosphorylation of tyrosine-phosphorylated proteins including protein tyrosine kinase Lyn, Fyn, and Syk and the appearance of a 28-kD tyrosine phosphorylated protein J Exp Med 179:1923-31

Xu, S; Gaskin, F (1994) Interaction of tubulin with guanosine 5'-O-(1-thiotriphosphate) diastereoisomers: specificity of the alpha-phosphate binding region. Biochemistry 33:11884-90

Faris, M; Gaskin, F; Geha, R S et al. (1993) Tyrosine phosphorylation defines a unique transduction pathway in human B cells mediated via CD40. Trans Assoc Am Physicians 106:187-95

Xu, S; Roychowdhury, S; Gaskin, F et al. (1992) Ethacrynic acid inhibition of microtubule assembly in vitro. Arch Biochem Biophys 296:462-7

Roychowdhury, S; Gaskin, F (1988) Stereoselectivity of the guanyl-exchangeable nucleotide-binding site of tubulin probed by guanosine 5'-O-(2-thiotriphosphate) diastereoisomers. Biochemistry 27:7799-805

Roychowdhury, S; Gaskin, F (1986) Magnesium requirements for guanosine 5'-O-(3-thiotriphosphate) induced assembly of microtubule protein and tubulin. Biochemistry 25:7847-53