Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
2R01NS026610-05A1
Application #
2265998
Study Section
Special Emphasis Panel (ZRG1-NLS-3 (01))
Project Start
1992-04-30
Project End
1999-05-31
Budget Start
1996-08-28
Budget End
1997-05-31
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Pittsburgh
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
053785812
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
Adler, S; Martinez, J; Williams, D S et al. (2000) Positive association between blood brain barrier disruption and osmotically-induced demyelination. Mult Scler 6:24-31
Adler, S; Verbalis, J G; Meyers, S et al. (2000) Changes in cerebral blood flow and distribution associated with acute increases in plasma sodium and osmolality of chronic hyponatremic rats. Exp Neurol 163:63-71
Baker, E A; Tian, Y; Adler, S et al. (2000) Blood-brain barrier disruption and complement activation in the brain following rapid correction of chronic hyponatremia. Exp Neurol 165:221-30
Adler, S; Verbalis, J G; Williams, D (1995) Effect of rapid correction of hyponatremia on the blood-brain barrier of rats. Brain Res 679:135-43
Adler, S; Verbalis, J G; Williams, D (1994) Brain buffering is restored in hyponatremic rats by correcting their plasma sodium concentration. J Am Soc Nephrol 5:85-92
Adler, S; Williams, D; Verbalis, J G (1993) Effect of acute and chronic hyponatremia on blood-brain barrier function in the rat. NMR Biomed 6:119-24
Adler, S; Verbalis, J G; Williams, D (1993) Effect of acute and chronic hyponatremia on brain buffering in rats. Am J Physiol 264:F968-74