Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS026884-07
Application #
2266181
Study Section
Neurology B Subcommittee 2 (NEUB)
Project Start
1988-12-01
Project End
1996-11-30
Budget Start
1994-12-01
Budget End
1996-11-30
Support Year
7
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Psychiatry
Type
Schools of Medicine
DUNS #
791277940
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Tamura, Yutaka; Ogita, Kiyokazu; Ueda, Tetsufumi (2014) A new VGLUT-specific potent inhibitor: pharmacophore of Brilliant Yellow. Neurochem Res 39:117-28
Winter, Harry C; Ueda, Tetsufumi (2008) The glutamate uptake system in presynaptic vesicles: further characterization of structural requirements for inhibitors and substrates. Neurochem Res 33:223-31
Amano, Taku; Matsubayashi, Hiroaki; Ozkan, Eric D et al. (2002) Aberrant reduction of an inhibitory protein factor in a rat epileptic model. Epilepsy Res 51:81-91
Tamura, Y; Ozkan, E D; Bole, D G et al. (2001) IPF, a vesicular uptake inhibitory protein factor, can reduce the Ca(2+)-dependent, evoked release of glutamate, GABA and serotonin. J Neurochem 76:1153-64
Ozkan, E D; Ueda, T (1998) Glutamate transport and storage in synaptic vesicles. Jpn J Pharmacol 77:1-10
Lewis, S M; Ueda, T (1998) Solubilization and reconstitution of synaptic vesicle glutamate transport system. Methods Enzymol 296:125-44
Lewis, S M; Lee, F S; Todorova, M et al. (1997) Synaptic vesicle glutamate uptake in epileptic (EL) mice. Neurochem Int 31:581-5
Ozkan, E D; Lee, F S; Ueda, T (1997) A protein factor that inhibits ATP-dependent glutamate and gamma-aminobutyric acid accumulation into synaptic vesicles: purification and initial characterization. Proc Natl Acad Sci U S A 94:4137-42
Tabb, J S; Kish, P E; Van Dyke, R et al. (1992) Glutamate transport into synaptic vesicles. Roles of membrane potential, pH gradient, and intravesicular pH. J Biol Chem 267:15412-8
Tabb, J S; Ueda, T (1991) Phylogenetic studies on the synaptic vesicle glutamate transport system. J Neurosci 11:1822-8

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