Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS029234-06
Application #
2267477
Study Section
Neurology C Study Section (NEUC)
Project Start
1991-01-01
Project End
1997-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Johns Hopkins University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Tucker, P C; Sack Jr, G H (2001) Expression of serum amyloid A genes in mouse brain: unprecedented response to inflammatory mediators. FASEB J 15:2241-6
Rowell, J F; Griffin, D E (1999) The inflammatory response to nonfatal Sindbis virus infection of the nervous system is more severe in SJL than in BALB/c mice and is associated with low levels of IL-4 mRNA and high levels of IL-10-producing CD4+ T cells. J Immunol 162:1624-32
Griffin, D E (1997) Cytokines in the brain during viral infection: clues to HIV-associated dementia. J Clin Invest 100:2948-51
Irani, D N; Lin, K I; Griffin, D E (1997) Regulation of brain-derived T cells during acute central nervous system inflammation. J Immunol 158:2318-26
Gorrell, M D; Lemm, J A; Rice, C M et al. (1997) Immunization with nonstructural proteins promotes functional recovery of alphavirus-infected neurons. J Virol 71:3415-9
Tucker, P C; Griffin, D E; Choi, S et al. (1996) Inhibition of nitric oxide synthesis increases mortality in Sindbis virus encephalitis. J Virol 70:3972-7
Griffin, D E (1996) The Gordon Wilson lecture: unique interactions between viruses, neurons and the immune system. Trans Am Clin Climatol Assoc 107:89-98
Mokhtarian, F; Wesselingh, S L; Choi, S et al. (1996) Production and role of cytokines in the CNS of mice with acute viral encephalomyelitis. J Neuroimmunol 66:11-22
Levine, B; Goldman, J E; Jiang, H H et al. (1996) Bc1-2 protects mice against fatal alphavirus encephalitis. Proc Natl Acad Sci U S A 93:4810-5
Despres, P; Griffin, J W; Griffin, D E (1995) Effects of anti-E2 monoclonal antibody on sindbis virus replication in AT3 cells expressing bcl-2. J Virol 69:7006-14

Showing the most recent 10 out of 20 publications