Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS029822-05
Application #
2267937
Study Section
Medical Biochemistry Study Section (MEDB)
Project Start
1991-07-01
Project End
1997-11-30
Budget Start
1995-12-18
Budget End
1996-11-30
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Indiana University-Purdue University at Indianapolis
Department
Pathology
Type
Schools of Medicine
DUNS #
005436803
City
Indianapolis
State
IN
Country
United States
Zip Code
46202

  Publications

Monaco, Salvatore; Fiorini, Michele; Farinazzo, Alessia et al. (2012) Allelic origin of protease-sensitive and protease-resistant prion protein isoforms in Gerstmann-Sträussler-Scheinker disease with the P102L mutation. PLoS One 7:e32382
Gambetti, Pierluigi; Kong, Qingzhong; Zou, Wenquan et al. (2003) Sporadic and familial CJD: classification and characterisation. Br Med Bull 66:213-39
Piccardo, P; Liepnieks, J J; William, A et al. (2001) Prion proteins with different conformations accumulate in Gerstmann-Straussler-Scheinker disease caused by A117V and F198S mutations. Am J Pathol 158:2201-7
Tagliavini, F; Lievens, P M; Tranchant, C et al. (2001) A 7-kDa prion protein (PrP) fragment, an integral component of the PrP region required for infectivity, is the major amyloid protein in Gerstmann-Straussler-Scheinker disease A117V. J Biol Chem 276:6009-15
Piccardo, P; Dlouhy, S R; Lievens, P M et al. (1998) Phenotypic variability of Gerstmann-Straussler-Scheinker disease is associated with prion protein heterogeneity. J Neuropathol Exp Neurol 57:979-88
Jimenez-Huete, A; Lievens, P M; Vidal, R et al. (1998) Endogenous proteolytic cleavage of normal and disease-associated isoforms of the human prion protein in neural and non-neural tissues. Am J Pathol 153:1561-72
Piccardo, P; Langeveld, J P; Hill, A F et al. (1998) An antibody raised against a conserved sequence of the prion protein recognizes pathological isoforms in human and animal prion diseases, including Creutzfeldt-Jakob disease and bovine spongiform encephalopathy. Am J Pathol 152:1415-20
Spillantini, M G; Bird, T D; Ghetti, B (1998) Frontotemporal dementia and Parkinsonism linked to chromosome 17: a new group of tauopathies. Brain Pathol 8:387-402
Spillantini, M G; Goedert, M; Crowther, R A et al. (1997) Familial multiple system tauopathy with presenile dementia: a disease with abundant neuronal and glial tau filaments. Proc Natl Acad Sci U S A 94:4113-8
Young, K; Clark, H B; Piccardo, P et al. (1997) Gerstmann-Straussler-Scheinker disease with the PRNP P102L mutation and valine at codon 129. Brain Res Mol Brain Res 44:147-50

Showing the most recent 10 out of 27 publications