Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
2R01NS030248-03A2
Application #
2037500
Study Section
Neurology A Study Section (NEUA)
Project Start
1991-09-30
Project End
1999-07-31
Budget Start
1996-09-30
Budget End
1997-07-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Kentucky
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
832127323
City
Lexington
State
KY
Country
United States
Zip Code
40506
Zwick, M; Teng, L; Mu, X et al. (2001) Overexpression of GDNF induces and maintains hyperinnervation of muscle fibers and multiple end-plate formation. Exp Neurol 171:342-50
Mu, X; Azbill, R D; Springer, J E (2000) Riluzole and methylprednisolone combined treatment improves functional recovery in traumatic spinal cord injury. J Neurotrauma 17:773-80
Azbill, R D; Mu, X; Springer, J E (2000) Riluzole increases high-affinity glutamate uptake in rat spinal cord synaptosomes. Brain Res 871:175-80
Mu, X; Azbill, R D; Springer, J E (2000) Riluzole improves measures of oxidative stress following traumatic spinal cord injury. Brain Res 870:66-72
Springer, J E; Azbill, R D; Knapp, P E (1999) Activation of the caspase-3 apoptotic cascade in traumatic spinal cord injury. Nat Med 5:943-6
Glazner, G W; Mu, X; Springer, J E (1998) Localization of glial cell line-derived neurotrophic factor receptor alpha and c-ret mRNA in rat central nervous system. J Comp Neurol 391:42-9
Springer, J E; Azbill, R D; Carlson, S L (1998) A rapid and sensitive assay for measuring mitochondrial metabolic activity in isolated neural tissue. Brain Res Brain Res Protoc 2:259-63
Azbill, R D; Mu, X; Bruce-Keller, A J et al. (1997) Impaired mitochondrial function, oxidative stress and altered antioxidant enzyme activities following traumatic spinal cord injury. Brain Res 765:283-90
Springer, J E; Azbill, R D; Mark, R J et al. (1997) 4-hydroxynonenal, a lipid peroxidation product, rapidly accumulates following traumatic spinal cord injury and inhibits glutamate uptake. J Neurochem 68:2469-76
Mu, X; Springer, J E; Bowser, R (1997) FAC1 expression and localization in motor neurons of developing, adult, and amyotrophic lateral sclerosis spinal cord. Exp Neurol 146:17-24

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