Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS030556-05
Application #
6187831
Study Section
Special Emphasis Panel (ZRG1-BDCN-2 (01))
Program Officer
Murphy, Diane
Project Start
1994-12-01
Project End
2002-08-31
Budget Start
2000-09-01
Budget End
2001-08-31
Support Year
5
Fiscal Year
2000
Total Cost
$365,553
Indirect Cost

  Institution

Name
Harvard University
Department
Psychiatry
Type
Schools of Medicine
DUNS #
082359691
City
Boston
State
MA
Country
United States
Zip Code
02115

  Publications

Madras, Bertha K; Fahey, Michele A; Goulet, Martin et al. (2006) Dopamine transporter (DAT) inhibitors alleviate specific parkinsonian deficits in monkeys: association with DAT occupancy in vivo. J Pharmacol Exp Ther 319:570-85
Jassen, Amy K; Brown, Jeffrey M; Panas, Helen N et al. (2005) Variants of the primate vesicular monoamine transporter-2. Brain Res Mol Brain Res 139:251-7
Madras, Bertha K; Miller, Gregory M; Fischman, Alan J (2002) The dopamine transporter: relevance to attention deficit hyperactivity disorder (ADHD). Behav Brain Res 130:57-63
Miller, G M; Madras, B K (2002) Polymorphisms in the 3'-untranslated region of human and monkey dopamine transporter genes affect reporter gene expression. Mol Psychiatry 7:44-55
Meschler, J P; Howlett, A C; Madras, B K (2001) Cannabinoid receptor agonist and antagonist effects on motor function in normal and 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP)-treated non-human primates. Psychopharmacology (Berl) 156:79-85
Goulet, M; Madras, B K (2000) D(1) dopamine receptor agonists are more effective in alleviating advanced than mild parkinsonism in 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine-treated monkeys. J Pharmacol Exp Ther 292:714-24
Bonab, A A; Fischman, A J; Alpert, N M (2000) Comparison of 4 methods for quantification of dopamine transporters by SPECT with [123I]IACFT. J Nucl Med 41:1086-92
Dougherty, D D; Bonab, A A; Spencer, T J et al. (1999) Dopamine transporter density in patients with attention deficit hyperactivity disorder. Lancet 354:2132-3
Madras, B K; Gracz, L M; Fahey, M A et al. (1998) Altropane, a SPECT or PET imaging probe for dopamine neurons: III. Human dopamine transporter in postmortem normal and Parkinson's diseased brain. Synapse 29:116-27
Madras, B K; Gracz, L M; Meltzer, P C et al. (1998) Altropane, a SPECT or PET imaging probe for dopamine neurons: II. Distribution to dopamine-rich regions of primate brain. Synapse 29:105-15

Showing the most recent 10 out of 17 publications