Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
7R01NS030791-02
Application #
2268756
Study Section
Neurological Sciences Subcommittee 1 (NLS)
Project Start
1994-07-01
Project End
1997-06-30
Budget Start
1995-04-01
Budget End
1995-06-30
Support Year
2
Fiscal Year
1994
Total Cost
Indirect Cost

  Institution

Name
Mallory Institute of Pathology
Department
Type
DUNS #
City
Boston
State
MA
Country
United States
Zip Code
02118

  Publications

Slack, Barbara E; Siniaia, Marina S; Blusztajn, Jan K (2006) Collagen type I selectively activates ectodomain shedding of the discoidin domain receptor 1: involvement of Src tyrosine kinase. J Cell Biochem 98:672-84
Lopez-Coviella, Ignacio; Mellott, Tiffany M; Kovacheva, Vesela P et al. (2006) Developmental pattern of expression of BMP receptors and Smads and activation of Smad1 and Smad5 by BMP9 in mouse basal forebrain. Brain Res 1088:49-56
Carey, Robyn M; Balcz, Brigitte A; Lopez-Coviella, Ignacio et al. (2005) Inhibition of dynamin-dependent endocytosis increases shedding of the amyloid precursor protein ectodomain and reduces generation of amyloid beta protein. BMC Cell Biol 6:30
Slack, Barbara E; Siniaia, Marina S (2005) Adhesion-dependent redistribution of MAP kinase and MEK promotes muscarinic receptor-mediated signaling to the nucleus. J Cell Biochem 95:366-78
Lopez-Coviella, Ignacio; Follettie, Maximillian T; Mellott, Tiffany J et al. (2005) Bone morphogenetic protein 9 induces the transcriptome of basal forebrain cholinergic neurons. Proc Natl Acad Sci U S A 102:6984-9
Slack, B E; Ma, L K; Seah, C C (2001) Constitutive shedding of the amyloid precursor protein ectodomain is up-regulated by tumour necrosis factor-alpha converting enzyme. Biochem J 357:787-94
Farber, S A; Slack, B E; Blusztajn, J K (2000) Acceleration of phosphatidylcholine synthesis and breakdown by inhibitors of mitochondrial function in neuronal cells: a model of the membrane defect of Alzheimer's disease. FASEB J 14:2198-206
Slack, B E (2000) The m3 muscarinic acetylcholine receptor is coupled to mitogen-activated protein kinase via protein kinase C and epidermal growth factor receptor kinase. Biochem J 348 Pt 2:381-7
Li, H; Leeman, S E; Slack, B E et al. (1997) A substance P (neurokinin-1) receptor mutant carboxyl-terminally truncated to resemble a naturally occurring receptor isoform displays enhanced responsiveness and resistance to desensitization. Proc Natl Acad Sci U S A 94:9475-80
Slack, B E; Breu, J; Muchnicki, L et al. (1997) Rapid stimulation of amyloid precursor protein release by epidermal growth factor: role of protein kinase C. Biochem J 327 ( Pt 1):245-9

Showing the most recent 10 out of 11 publications