Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
7R01NS031556-02
Application #
2685693
Study Section
Neurological Sciences Subcommittee 1 (NLS)
Program Officer
Kerza-Kwiatecki, a P
Project Start
1997-04-01
Project End
2000-03-31
Budget Start
1998-02-01
Budget End
1998-03-31
Support Year
2
Fiscal Year
1997
Total Cost
Indirect Cost
Name
University of Illinois at Chicago
Department
Anesthesiology
Type
Schools of Medicine
DUNS #
121911077
City
Chicago
State
IL
Country
United States
Zip Code
60612
Madrigal, Jose L M; Feinstein, Douglas L; Dello Russo, Cinzia (2005) Norepinephrine protects cortical neurons against microglial-induced cell death. J Neurosci Res 81:390-6
Heneka, Michael T; Gavrilyuk, Vitaliy; Landreth, Gary E et al. (2003) Noradrenergic depletion increases inflammatory responses in brain: effects on IkappaB and HSP70 expression. J Neurochem 85:387-98
Bhat, Narayan R; Feinstein, Douglas L; Shen, Qin et al. (2002) p38 MAPK-mediated transcriptional activation of inducible nitric-oxide synthase in glial cells. Roles of nuclear factors, nuclear factor kappa B, cAMP response element-binding protein, CCAAT/enhancer-binding protein-beta, and activating transcription fact J Biol Chem 277:29584-92
Heneka, Michael T; Galea, Elena; Gavriluyk, Vitaliy et al. (2002) Noradrenergic depletion potentiates beta -amyloid-induced cortical inflammation: implications for Alzheimer's disease. J Neurosci 22:2434-42
Murphy, Patricia; Sharp, Anthony; Shin, Joseph et al. (2002) Suppressive effects of ansamycins on inducible nitric oxide synthase expression and the development of experimental autoimmune encephalomyelitis. J Neurosci Res 67:461-70
Feinstein, D L; Murphy, P; Sharp, A et al. (2001) Local anesthetics potentiate nitric oxide synthase type 2 expression in rat glial cells. J Neurosurg Anesthesiol 13:99-105
Gavrilyuk, V; Horvath, P; Weinberg, G et al. (2001) A 27-bp region of the inducible nitric oxide synthase promoter regulates expression in glial cells. J Neurochem 78:129-40
Heneka, M T; Feinstein, D L (2001) Expression and function of inducible nitric oxide synthase in neurons. J Neuroimmunol 114:8-18
Heneka, M T; Sharp, A; Murphy, P et al. (2001) The heat shock response reduces myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis in mice. J Neurochem 77:568-79
Heneka, M T; Klockgether, T; Feinstein, D L (2000) Peroxisome proliferator-activated receptor-gamma ligands reduce neuronal inducible nitric oxide synthase expression and cell death in vivo. J Neurosci 20:6862-7

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