Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS032207-03
Application #
2270223
Study Section
AIDS and Related Research Study Section 7 (ARRG)
Project Start
1993-12-01
Project End
1997-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of Texas Sw Medical Center Dallas
Department
Obstetrics & Gynecology
Type
Schools of Medicine
DUNS #
City
Dallas
State
TX
Country
United States
Zip Code
75390

  Publications

Barnea, A; Roberts, J; Ho, R H (1999) Evidence for a synergistic effect of the HIV-1 envelope protein gp120 and brain-derived neurotrophic factor (BDNF) leading to enhanced expression of somatostatin neurons in aggregate cultures derived from the human fetal cortex. Brain Res 815:349-57
Barnea, A; Roberts, J (1999) An improved method for dissociation and aggregate culture of human fetal brain cells in serum-free medium. Brain Res Brain Res Protoc 4:156-64
Barnea, A; Aguila-Mansilla, N; Bigio, E H et al. (1998) Evidence for regulated expression of neuropeptide Y gene by rat and human cultured astrocytes. Regul Pept 75-76:293-300
Barnea, A; Aguila-Mansilla, N; Lu, G et al. (1997) Opposite effects of astrocyte-derived soluble factor(s) on the functional expression of fetal peptidergic neurons in aggregate cultures: enhancement of neuropeptide Y and suppression of somatostatin. J Neurosci Res 50:605-17
Aguila-Mansilla, N; Little, B B; Ho, R H et al. (1997) Differential potencies of cocaine and its metabolites, cocaethylene and benzoylecgonine, in suppressing the functional expression of somatostatin and neuropeptide Y producing neurons in cultures of fetal cortical cells. Biochem Pharmacol 54:491-500
Aguila-Mansilla, N; Barnea, A (1996) Human fetal brain cells in aggregate culture: a model system to study regulatory processes of the developing human neuropeptide Y (NPY)-producing neuron. Int J Dev Neurosci 14:531-9
Barnea, A; Aguila-Mansilla, N; Chute, H T et al. (1996) Comparison of neurotrophin regulation of human and rat neuropeptide Y (NPY) neurons: induction of NPY production in aggregate cultures derived from rat but not from human fetal brains. Brain Res 732:52-60
Barnea, A; Cho, G; Lu, G et al. (1995) Brain-derived neurotrophic factor induces functional expression and phenotypic differentiation of cultured fetal neuropeptide Y-producing neurons. J Neurosci Res 42:638-47