Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS032321-03
Application #
2270410
Study Section
Neurology A Study Section (NEUA)
Project Start
1994-09-01
Project End
1998-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Medical College of Wisconsin
Department
Type
Organized Research Units
DUNS #
073134603
City
Milwaukee
State
WI
Country
United States
Zip Code
53226
Medhora, Meetha; Daniels, John; Mundey, Kavita et al. (2003) Epoxygenase-driven angiogenesis in human lung microvascular endothelial cells. Am J Physiol Heart Circ Physiol 284:H215-24
Bylund, Johan; Harder, Adam G; Maier, Kristopher G et al. (2003) Leukotriene B4 omega-side chain hydroxylation by CYP4F5 and CYP4F6. Arch Biochem Biophys 412:34-41
Liu, Yanping; Harder, David R; Lombard, Julian H (2002) Interaction of myogenic mechanisms and hypoxic dilation in rat middle cerebral arteries. Am J Physiol Heart Circ Physiol 283:H2276-81
Bylund, Johan; Zhang, Chenyang; Harder, David R (2002) Identification of a novel cytochrome P450, CYP4X1, with unique localization specific to the brain. Biochem Biophys Res Commun 296:677-84
Medhora, Meetha; Bousamra 2nd, Michael; Zhu, Daling et al. (2002) Upregulation of collagens detected by gene array in a model of flow-induced pulmonary vascular remodeling. Am J Physiol Heart Circ Physiol 282:H414-22
Nithipatikom, K; Grall, A J; Holmes, B B et al. (2001) Liquid chromatographic-electrospray ionization-mass spectrometric analysis of cytochrome P450 metabolites of arachidonic acid. Anal Biochem 298:327-36
Medhora, M; Narayanan, J; Harder, D (2001) Dual regulation of the cerebral microvasculature by epoxyeicosatrienoic acids. Trends Cardiovasc Med 11:38-42
Medhora, M; Narayanan, J; Harder, D et al. (2001) Identifying endothelium-derived hyperpolarizing factor: recent approaches to assay the role of epoxyeicosatrienoic acids. Jpn J Pharmacol 86:369-75
Gebremedhin, D; Lange, A R; Lowry, T F et al. (2000) Production of 20-HETE and its role in autoregulation of cerebral blood flow. Circ Res 87:60-5
Medhora, M; Harder, D (1998) Functional role of epoxyeicosatrienoic acids and their production in astrocytes: approaches for gene transfer and therapy (review). Int J Mol Med 2:661-9

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