Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS032470-03
Application #
2270699
Study Section
Neurological Sciences Subcommittee 1 (NLS)
Project Start
1994-01-01
Project End
1997-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Texas Health Science Center Houston
Department
Neurosciences
Type
Schools of Medicine
DUNS #
City
Houston
State
TX
Country
United States
Zip Code
77225
Kelly, Paul T; Mackinnon 2nd, Roger L; Dietz, Roger V et al. (2005) Postsynaptic IP3 receptor-mediated Ca2+ release modulates synaptic transmission in hippocampal neurons. Brain Res Mol Brain Res 135:232-48
Maher, Brady J; Mackinnon 2nd, Roger L; Bai, Jihong et al. (2005) Activation of postsynaptic Ca(2+) stores modulates glutamate receptor cycling in hippocampal neurons. J Neurophysiol 93:178-88
Wang, J H; Kelly, P (2001) Calcium-calmodulin signalling pathway up-regulates glutamatergic synaptic function in non-pyramidal, fast spiking rat hippocampal CA1 neurons. J Physiol 533:407-22
Ko, G Y; Kelly, P T (1999) Nitric oxide acts as a postsynaptic signaling molecule in calcium/calmodulin-induced synaptic potentiation in hippocampal CA1 pyramidal neurons. J Neurosci 19:6784-94
Wang, J H; Kelly, P T (1997) Postsynaptic calcineurin activity downregulates synaptic transmission by weakening intracellular Ca2+ signaling mechanisms in hippocampal CA1 neurons. J Neurosci 17:4600-11
Wang, J H; Kelly, P T (1997) Attenuation of paired-pulse facilitation associated with synaptic potentiation mediated by postsynaptic mechanisms. J Neurophysiol 78:2707-16
Wang, J H; Kelly, P T (1996) The balance between postsynaptic Ca(2+)-dependent protein kinase and phosphatase activities controlling synaptic strength. Learn Mem 3:170-81
Wang, J H; Kelly, P T (1996) Regulation of synaptic facilitation by postsynaptic Ca2+/CaM pathways in hippocampal CA1 neurons. J Neurophysiol 76:276-86
Wang, J H; Kelly, P T (1995) Postsynaptic injection of CA2+/CaM induces synaptic potentiation requiring CaMKII and PKC activity. Neuron 15:443-52
Huber, K M; Mauk, M D; Kelly, P T (1995) Distinct LTP induction mechanisms: contribution of NMDA receptors and voltage-dependent calcium channels. J Neurophysiol 73:270-9

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