Neurotrophic Factors in Spinal Cord Trauma

Mocchetti, Italo

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Neurological Disorders and Stroke (NINDS)
• Type: Research Project (R01)
• Project #: 5R01NS032671-03
• Application #: 2271016
• Study Section: Neurology B Subcommittee 2 (NEUB)
• Program Officer: Cheung, Mary Ellen
• Project Start: 1994-09-30
• Project End: 1998-08-31
• Budget Start: 1996-09-01
• Budget End: 1998-08-31
• Support Year: 3
• Fiscal Year: 1996

Institution

• Name: Georgetown University
• Department: Anatomy/Cell Biology
• Type: Schools of Medicine
• DUNS #: 049515844
• City: Washington
• State: DC
• Country: United States
• Zip Code: 20057

Publications

Brandoli, C; Shi, B; Pflug, B et al. (2001) Dexamethasone reduces the expression of p75 neurotrophin receptor and apoptosis in contused spinal cord. Brain Res Mol Brain Res 87:61-70

Brandoli, C; Sanna, A; De Bernardi, M A et al. (1998) Brain-derived neurotrophic factor and basic fibroblast growth factor downregulate NMDA receptor function in cerebellar granule cells. J Neurosci 18:7953-61

Marini, A M; Rabin, S J; Lipsky, R H et al. (1998) Activity-dependent release of brain-derived neurotrophic factor underlies the neuroprotective effect of N-methyl-D-aspartate. J Biol Chem 273:29394-9

Follesa, P; Wrathall, J R; Mocchetti, I (1998) 2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(F)-quinoxaline (NBQX) increases fibroblast growth factor mRNA levels after contusive spinal cord injury. Brain Res 782:306-9

Wang, C X; Olschowka, J A; Wrathall, J R (1997) Increase of interleukin-1beta mRNA and protein in the spinal cord following experimental traumatic injury in the rat. Brain Res 759:190-6

Mocchetti, I; Rabin, S J; Colangelo, A M et al. (1996) Increased basic fibroblast growth factor expression following contusive spinal cord injury. Exp Neurol 141:154-64

Mocchetti, I; Wrathall, J R (1995) Neurotrophic factors in central nervous system trauma. J Neurotrauma 12:853-70