Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS033347-02
Application #
2272112
Study Section
Nutrition Study Section (NTN)
Program Officer
Kitt, Cheryl A
Project Start
1995-06-01
Project End
1999-05-31
Budget Start
1996-06-01
Budget End
1997-05-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of California Davis
Department
Anatomy/Cell Biology
Type
Schools of Veterinary Medicine
DUNS #
094878337
City
Davis
State
CA
Country
United States
Zip Code
95618
Gietzen, Dorothy W; Aja, Susan M (2012) The brain's response to an essential amino acid-deficient diet and the circuitous route to a better meal. Mol Neurobiol 46:332-48
Rudell, John B; Rechs, Adam J; Kelman, Todd J et al. (2011) The anterior piriform cortex is sufficient for detecting depletion of an indispensable amino acid, showing independent cortical sensory function. J Neurosci 31:1583-90
Hao, S; Ross-Inta, C M; Gietzen, D W (2010) The sensing of essential amino acid deficiency in the anterior piriform cortex, that requires the uncharged tRNA/GCN2 pathway, is sensitive to wortmannin but not rapamycin. Pharmacol Biochem Behav 94:333-40
Gietzen, Dorothy W; Hao, Shuzhen; Anthony, Tracy G (2007) Mechanisms of food intake repression in indispensable amino acid deficiency. Annu Rev Nutr 27:63-78
Gietzen, Dorothy W; Rogers, Quinton R (2006) Nutritional homeostasis and indispensable amino acid sensing: a new solution to an old puzzle. Trends Neurosci 29:91-9
Sharp, James W; Ross-Inta, Catherine M; Hao, Shuzhen et al. (2006) Co-localization of phosphorylated extracellular signal-regulated protein kinases 1/2 (ERK1/2) and phosphorylated eukaryotic initiation factor 2alpha (eIF2alpha) in response to a threonine-devoid diet. J Comp Neurol 494:485-94
Bellinger, Larry L; Williams, Fred E; Lucente, James et al. (2005) Autonomic efferents affect intake of imbalanced amino acid diets by rats. Pharmacol Biochem Behav 81:24-31
Hao, Shuzhen; Sharp, James W; Ross-Inta, Catherine M et al. (2005) Uncharged tRNA and sensing of amino acid deficiency in mammalian piriform cortex. Science 307:1776-8
Koehnle, Thomas J; Russell, Matthew C; Morin, Andrew S et al. (2004) Diets deficient in indispensable amino acids rapidly decrease the concentration of the limiting amino acid in the anterior piriform cortex of rats. J Nutr 134:2365-71
Blevins, J Ernie; Truong, Ban G; Gietzen, Dorothy W (2004) NMDA receptor function within the anterior piriform cortex and lateral hypothalamus in rats on the control of intake of amino acid-deficient diets. Brain Res 1019:124-33

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