Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
7R01NS033354-02
Application #
2393123
Study Section
Mammalian Genetics Study Section (MGN)
Project Start
1996-04-01
Project End
2001-03-31
Budget Start
1996-09-01
Budget End
1997-03-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
City of Hope/Beckman Research Institute
Department
Type
DUNS #
City
Duarte
State
CA
Country
United States
Zip Code
91010
Hill, Kathleen A; Buettner, Victoria L; Heidt, Analeah et al. (2006) Most spontaneous tumors in a mouse model of Li-Fraumeni syndrome do not have a mutator phenotype. Carcinogenesis 27:1860-6
Hill, Kathleen A; Halangoda, Asanga; Heinmoeller, Petra W et al. (2005) Tissue-specific time courses of spontaneous mutation frequency and deviations in mutation pattern are observed in middle to late adulthood in Big Blue mice. Environ Mol Mutagen 45:442-54
Hill, Kathleen A; Wang, Jicheng; Farwell, Kelly D et al. (2003) Spontaneous tandem-base mutations (TBM) show dramatic tissue, age, pattern and spectrum specificity. Mutat Res 534:173-86
Hill, Kathleen A; Sommer, Steve S (2002) p53 as a mutagen test in breast cancer. Environ Mol Mutagen 39:216-27
Kunishige, M; Hill, K A; Riemer, A M et al. (2001) Mutation frequency is reduced in the cerebellum of Big Blue mice overexpressing a human wild type SOD1 gene. Mutat Res 473:139-49
Weinshenker, B G; Sommer, S (2001) VAPSE-based analysis: a two-phased candidate gene approach for elucidating genetic predisposition to complex disorders. Mutat Res 458:7-17
Halangoda, A; Still, J G; Hill, K A et al. (2001) Spontaneous microdeletions and microinsertions in a transgenic mouse mutation detection system: analysis of age, tissue, and sequence specificity. Environ Mol Mutagen 37:311-23
Buettner, V L; Hill, K A; Scaringe, W A et al. (2000) Evidence that proximal multiple mutations in Big Blue transgenic mice are dependent events. Mutat Res 452:219-29
Moore, S R; Hill, K A; Heinmoller, P W et al. (1999) Spontaneous mutation frequency and pattern in Big Blue mice fed a vitamin E-supplemented diet. Environ Mol Mutagen 34:195-200
Hill, K A; Nishino, H; Buettner, V L et al. (1999) The Big Blue(R) transgenic mouse mutation detection assay: the mutation pattern of sectored mutant plaques. Mutat Res 425:47-54

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