Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
7R01NS033373-02
Application #
2272156
Study Section
Pharmacology A Study Section (PHRA)
Project Start
1994-08-01
Project End
1998-07-31
Budget Start
1995-04-01
Budget End
1995-07-31
Support Year
2
Fiscal Year
1994
Total Cost
Indirect Cost
Name
Vanderbilt University Medical Center
Department
Pharmacology
Type
Schools of Medicine
DUNS #
004413456
City
Nashville
State
TN
Country
United States
Zip Code
37212
Jayanthi, L D; Wilson, J J; Montalvo, J et al. (2000) Differential regulation of mammalian brain-specific proline transporter by calcium and calcium-dependent protein kinases. Br J Pharmacol 129:465-70
Galli, A; Jayanthi, L D; Ramsey, I S et al. (1999) L-proline and L-pipecolate induce enkephalin-sensitive currents in human embryonic kidney 293 cells transfected with the high-affinity mammalian brain L-proline transporter. J Neurosci 19:6290-7
Jayanthi, L D; Apparsundaram, S; Malone, M D et al. (1998) The Caenorhabditis elegans gene T23G5.5 encodes an antidepressant- and cocaine-sensitive dopamine transporter. Mol Pharmacol 54:601-9
Apparsundaram, S; Galli, A; DeFelice, L J et al. (1998) Acute regulation of norepinephrine transport: I. protein kinase C-linked muscarinic receptors influence transport capacity and transporter density in SK-N-SH cells. J Pharmacol Exp Ther 287:733-43
Fritz, J D; Jayanthi, L D; Thoreson, M A et al. (1998) Cloning and chromosomal mapping of the murine norepinephrine transporter. J Neurochem 70:2241-51
Apparsundaram, S; Schroeter, S; Giovanetti, E et al. (1998) Acute regulation of norepinephrine transport: II. PKC-modulated surface expression of human norepinephrine transporter proteins. J Pharmacol Exp Ther 287:744-51
Galli, A; Blakely, R D; DeFelice, L J (1998) Patch-clamp and amperometric recordings from norepinephrine transporters: channel activity and voltage-dependent uptake. Proc Natl Acad Sci U S A 95:13260-5
Ramamoorthy, S; Melikian, H E; Qian, Y et al. (1998) Biosynthesis, N-glycosylation, and surface trafficking of biogenic amine transporter proteins. Methods Enzymol 296:347-70
Zhu, M Y; Blakely, R D; Apparsundaram, S et al. (1998) Down-regulation of the human norepinephrine transporter in intact 293-hNET cells exposed to desipramine. J Neurochem 70:1547-55
Eshleman, A J; Stewart, E; Evenson, A K et al. (1997) Metabolism of catecholamines by catechol-O-methyltransferase in cells expressing recombinant catecholamine transporters. J Neurochem 69:1459-66

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