Glutamate in Parkinsons Disease

Greenamyre, J Timothy

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Neurological Disorders and Stroke (NINDS)
• Type: Research Project (R01)
• Project #: 5R01NS033779-03
• Application #: 2272771
• Study Section: Neurology A Study Section (NEUA)
• Project Start: 1995-01-01
• Project End: 1999-12-31
• Budget Start: 1996-01-01
• Budget End: 1996-12-31
• Support Year: 3
• Fiscal Year: 1996

Institution

• Name: Emory University
• Department: Neurology
• Type: Schools of Medicine
• DUNS #: 042250712
• City: Atlanta
• State: GA
• Country: United States
• Zip Code: 30322

Publications

Betarbet, Ranjita; Poisik, Olga; Sherer, Todd B et al. (2004) Differential expression and ser897 phosphorylation of striatal N-methyl-d-aspartate receptor subunit NR1 in animal models of Parkinson's disease. Exp Neurol 187:76-85

Betarbet, Ranjita; Greenamyre, J Timothy (2004) Regulation of dopamine receptor and neuropeptide expression in the basal ganglia of monkeys treated with MPTP. Exp Neurol 189:393-403

Betarbet, Ranjita; Sherer, Todd B; Greenamyre, J Timothy (2002) Animal models of Parkinson's disease. Bioessays 24:308-18

Sherer, Todd B; Betarbet, Ranjita; Greenamyre, J Timothy (2002) Environment, mitochondria, and Parkinson's disease. Neuroscientist 8:192-7

Blandini, F; Nappi, G; Greenamyre, J T (2001) Subthalamic infusion of an NMDA antagonist prevents basal ganglia metabolic changes and nigral degeneration in a rodent model of Parkinson's disease. Ann Neurol 49:525-9

Greenamyre, J T (2001) Glutamatergic influences on the basal ganglia. Clin Neuropharmacol 24:65-70

Greenamyre, J T; Sherer, T B; Betarbet, R et al. (2001) Complex I and Parkinson's disease. IUBMB Life 52:135-41

Betarbet, R; Sherer, T B; MacKenzie, G et al. (2000) Chronic systemic pesticide exposure reproduces features of Parkinson's disease. Nat Neurosci 3:1301-6

Greenamyre, J T (2000) ""Ottorino Rossi"" Award 2000. New targets for therapy in Parkinson's disease: pathogenesis and pathophysiology. Funct Neurol 15:67-80

Steece-Collier, K; Chambers, L K; Jaw-Tsai, S S et al. (2000) Antiparkinsonian actions of CP-101,606, an antagonist of NR2B subunit-containing N-methyl-d-aspartate receptors. Exp Neurol 163:239-43