Viral and Cellular Determinants Involved in CNS Disease

Fujinami, Robert S.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Neurological Disorders and Stroke (NINDS)
• Type: Research Project (R01)
• Project #: 5R01NS034497-02
• Application #: 2273748
• Study Section: Neurology C Study Section (NEUC)
• Project Start: 1995-08-01
• Project End: 1999-05-31
• Budget Start: 1996-06-01
• Budget End: 1997-05-31
• Support Year: 2
• Fiscal Year: 1996

Institution

• Name: University of Utah
• Department: Neurology
• Type: Schools of Medicine
• City: Salt Lake City
• State: UT
• Country: United States
• Zip Code: 84112

Publications

Tsunoda, Ikuo; Libbey, Jane E; Fujinami, Robert S (2012) Immunization with structural and non-structural proteins of Theiler's murine encephalomyelitis virus alters demyelinating disease. J Neurovirol 18:127-37

Libbey, Jane E; Cusick, Matthew F; Tsunoda, Ikuo et al. (2012) Antiviral CD8? T cells cause an experimental autoimmune encephalomyelitis-like disease in naive mice. J Neurovirol 18:45-54

Tsunoda, Ikuo; Tanaka, Tomoko; Taniguchi, Masaru et al. (2009) Contrasting roles for Valpha14+ natural killer T cells in a viral model for multiple sclerosis. J Neurovirol 15:90-8

Tsunoda, Ikuo; Libbey, Jane E; Fujinami, Robert S (2009) Theiler's murine encephalomyelitis virus attachment to the gastrointestinal tract is associated with sialic acid binding. J Neurovirol 15:81-9

Tsunoda, Ikuo; Tanaka, Tomoko; Fujinami, Robert S (2008) Regulatory role of CD1d in neurotropic virus infection. J Virol 82:10279-89

Tsunoda, Ikuo; Tanaka, Tomoko; Terry, Emily Jane et al. (2007) Contrasting roles for axonal degeneration in an autoimmune versus viral model of multiple sclerosis: When can axonal injury be beneficial? Am J Pathol 170:214-26

Tsunoda, Ikuo; Libbey, Jane E; Fujinami, Robert S (2007) TGF-beta1 suppresses T cell infiltration and VP2 puff B mutation enhances apoptosis in acute polioencephalitis induced by Theiler's virus. J Neuroimmunol 190:80-9

Tsunoda, Ikuo; Tanaka, Tomoko; Saijoh, Yukio et al. (2007) Targeting inflammatory demyelinating lesions to sites of Wallerian degeneration. Am J Pathol 171:1563-75

Libbey, Jane E; Tsunoda, Ikuo; Whitton, J Lindsay et al. (2007) Infectious RNA isolated from the spinal cords of mice chronically infected with Theiler's murine encephalomyelitis virus. J Virol 81:3009-11

Carlson, Noel G; Hill, Kenneth E; Tsunoda, Ikuo et al. (2006) The pathologic role for COX-2 in apoptotic oligodendrocytes in virus induced demyelinating disease: implications for multiple sclerosis. J Neuroimmunol 174:21-31