Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
1R01NS034813-01A1
Application #
2038131
Study Section
Neurological Sciences Subcommittee 1 (NLS)
Project Start
1996-07-22
Project End
2001-05-31
Budget Start
1996-07-22
Budget End
1997-05-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Yale University
Department
Neurology
Type
Schools of Medicine
DUNS #
082359691
City
New Haven
State
CT
Country
United States
Zip Code
06520
Patel, Anant B; Lai, James C K; Chowdhury, Golam I M et al. (2017) Comparison of Glutamate Turnover in Nerve Terminals and Brain Tissue During [1,6-13C2]Glucose Metabolism in Anesthetized Rats. Neurochem Res 42:173-190
Patel, Anant B; de Graaf, Robin A; Rothman, Douglas L et al. (2015) Effects of ?-Aminobutyric acid transporter 1 inhibition by tiagabine on brain glutamate and ?-Aminobutyric acid metabolism in the anesthetized rat In vivo. J Neurosci Res 93:1101-8
Malthankar-Phatak, Gauri H; Patel, Anant B; Xia, Ying et al. (2008) Effects of continuous hypoxia on energy metabolism in cultured cerebro-cortical neurons. Brain Res 1229:147-54
Chowdhury, Golam M I; Patel, Anant B; Mason, Graeme F et al. (2007) Glutamatergic and GABAergic neurotransmitter cycling and energy metabolism in rat cerebral cortex during postnatal development. J Cereb Blood Flow Metab 27:1895-907
Chowdhury, G M I; Gupta, M; Gibson, K M et al. (2007) Altered cerebral glucose and acetate metabolism in succinic semialdehyde dehydrogenase-deficient mice: evidence for glial dysfunction and reduced glutamate/glutamine cycling. J Neurochem 103:2077-91
Patel, Anant B; de Graaf, Robin A; Martin, David L et al. (2006) Evidence that GAD65 mediates increased GABA synthesis during intense neuronal activity in vivo. J Neurochem 97:385-96
Kida, Ikuhiro; Smith, Arien J; Blumenfeld, Hal et al. (2006) Lamotrigine suppresses neurophysiological responses to somatosensory stimulation in the rodent. Neuroimage 29:216-24
de Graaf, Robin A; Patel, Anant B; Rothman, Douglas L et al. (2006) Acute regulation of steady-state GABA levels following GABA-transaminase inhibition in rat cerebral cortex. Neurochem Int 48:508-14
Malthankar-Phatak, Gauri H; de Lanerolle, Nihal; Eid, Tore et al. (2006) Differential glutamate dehydrogenase (GDH) activity profile in patients with temporal lobe epilepsy. Epilepsia 47:1292-9
Hyder, Fahmeed; Patel, Anant B; Gjedde, Albert et al. (2006) Neuronal-glial glucose oxidation and glutamatergic-GABAergic function. J Cereb Blood Flow Metab 26:865-77

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