Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
1R01NS034857-01A1
Application #
2274167
Study Section
Neurological Sciences Subcommittee 1 (NLS)
Program Officer
Kitt, Cheryl A
Project Start
1996-09-01
Project End
1999-07-31
Budget Start
1996-09-01
Budget End
1997-07-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Tennessee Health Science Center
Department
Physiology
Type
Schools of Medicine
DUNS #
941884009
City
Memphis
State
TN
Country
United States
Zip Code
38163
Li, Shuxin; Dou, Wenkai; Tang, Ying et al. (2008) Acetaminophen: antipyretic or hypothermic in mice? In either case, PGHS-1b (COX-3) is irrelevant. Prostaglandins Other Lipid Mediat 85:89-99
Blatteis, Clark M (2007) The onset of fever: new insights into its mechanism. Prog Brain Res 162:3-14
Feleder, Carlos; Perlik, Vit; Blatteis, Clark M (2007) Preoptic nitric oxide attenuates endotoxic fever in guinea pigs by inhibiting the POA release of norepinephrine. Am J Physiol Regul Integr Comp Physiol 293:R1144-51
Feleder, Carlos; Perlik, Vit; Blatteis, Clark M (2007) Preoptic norepinephrine mediates the febrile response of guinea pigs to lipopolysaccharide. Am J Physiol Regul Integr Comp Physiol 293:R1135-43
Blatteis, Clark M (2006) Endotoxic fever: new concepts of its regulation suggest new approaches to its management. Pharmacol Ther 111:194-223
Li, Zhonghua; Perlik, Vit; Feleder, Carlos et al. (2006) Kupffer cell-generated PGE2 triggers the febrile response of guinea pigs to intravenously injected LPS. Am J Physiol Regul Integr Comp Physiol 290:R1262-70
Perlik, Vit; Li, Zhongua; Goorha, Sarita et al. (2005) LPS-activated complement, not LPS per se, triggers the early release of PGE2 by Kupffer cells. Am J Physiol Regul Integr Comp Physiol 289:R332-R339
Blatteis, Clark M; Li, Shuxin; Li, Zhonghua et al. (2005) Cytokines, PGE2 and endotoxic fever: a re-assessment. Prostaglandins Other Lipid Mediat 76:1-18
Li, S; Boackle, S A; Holers, V M et al. (2005) Complement component c5a is integral to the febrile response of mice to lipopolysaccharide. Neuroimmunomodulation 12:67-80
Feleder, Carlos; Perlik, Vit; Tang, Ying et al. (2005) Putative antihyperpyretic factor induced by LPS in spleen of guinea pigs. Am J Physiol Regul Integr Comp Physiol 289:R680-7

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