Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
3R01NS034951-01A1S1
Application #
2447003
Study Section
Special Emphasis Panel (ZRG1-NLS-3 (01))
Project Start
1996-08-15
Project End
2001-07-31
Budget Start
1996-08-15
Budget End
1997-07-31
Support Year
1
Fiscal Year
1997
Total Cost
Indirect Cost
Name
University of Miami School of Medicine
Department
Pathology
Type
Schools of Medicine
DUNS #
City
Miami
State
FL
Country
United States
Zip Code
33146
Jayakumar, A R; Rama Rao, K V; Kalaiselvi, P et al. (2004) Combined effects of ammonia and manganese on astrocytes in culture. Neurochem Res 29:2051-6
Rama Rao, K V; Jayakumar, A R; Norenberg, M D (2003) Induction of the mitochondrial permeability transition in cultured astrocytes by glutamine. Neurochem Int 43:517-23
Rama Rao, K V; Chen, M; Simard, J M et al. (2003) Increased aquaporin-4 expression in ammonia-treated cultured astrocytes. Neuroreport 14:2379-82
Rama Rao, K V; Chen, M; Simard, J M et al. (2003) Suppression of ammonia-induced astrocyte swelling by cyclosporin A. J Neurosci Res 74:891-7
Rama Rao, K V; Jayakumar, A R; Norenberg, D M (2003) Ammonia neurotoxicity: role of the mitochondrial permeability transition. Metab Brain Dis 18:113-27
Jayakumar, A R; Panickar, K S; Norenberg, M D (2002) Effects on free radical generation by ligands of the peripheral benzodiazepine receptor in cultured neural cells. J Neurochem 83:1226-34
Murthy, Chinta R K; Norenberg, Michael D (2002) Suppression of ammonia-induced swelling by aspartate but not by ornithine in primary cultures of rat astrocytes. Neurochem Int 41:171-6
Murthy, C R; Rama Rao, K V; Bai, G et al. (2001) Ammonia-induced production of free radicals in primary cultures of rat astrocytes. J Neurosci Res 66:282-8
Bai, G; Rama Rao, K V; Murthy, C R et al. (2001) Ammonia induces the mitochondrial permeability transition in primary cultures of rat astrocytes. J Neurosci Res 66:981-91
Murthy, C R; Bender, A S; Dombro, R S et al. (2000) Elevation of glutathione levels by ammonium ions in primary cultures of rat astrocytes. Neurochem Int 37:255-68

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