Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
2R01NS035566-04
Application #
2911164
Study Section
Special Emphasis Panel (ZRG1-MDCN-6 (01))
Program Officer
Leblanc, Gabrielle G
Project Start
1996-09-01
Project End
2003-06-30
Budget Start
1999-07-19
Budget End
2000-06-30
Support Year
4
Fiscal Year
1999
Total Cost
Indirect Cost
Name
Northwestern University at Chicago
Department
Pharmacology
Type
Schools of Medicine
DUNS #
005436803
City
Chicago
State
IL
Country
United States
Zip Code
60611
Berechid, Bridget E; Kitzmann, Magali; Foltz, Daniel R et al. (2002) Identification and characterization of presenilin-independent Notch signaling. J Biol Chem 277:8154-65
Foltz, Daniel R; Santiago, Michelle C; Berechid, Bridget E et al. (2002) Glycogen synthase kinase-3beta modulates notch signaling and stability. Curr Biol 12:1006-11
Presente, A; Andres, A; Nye, J S (2001) Requirement of Notch in adulthood for neurological function and longevity. Neuroreport 12:3321-5
Chambers, C B; Peng, Y; Nguyen, H et al. (2001) Spatiotemporal selectivity of response to Notch1 signals in mammalian forebrain precursors. Development 128:689-702
Foltz, D R; Nye, J S (2001) Hyperphosphorylation and association with RBP of the intracellular domain of Notch1. Biochem Biophys Res Commun 286:484-92
Gaiano, N; Nye, J S; Fishell, G (2000) Radial glial identity is promoted by Notch1 signaling in the murine forebrain. Neuron 26:395-404
Palacino, J J; Berechid, B E; Alexander, P et al. (2000) Regulation of amyloid precursor protein processing by presenilin 1 (PS1) and PS2 in PS1 knockout cells. J Biol Chem 275:215-22
Berechid, B E; Thinakaran, G; Wong, P C et al. (1999) Lack of requirement for presenilin1 in Notch1 signaling. Curr Biol 9:1493-6
Franklin, J L; Berechid, B E; Cutting, F B et al. (1999) Autonomous and non-autonomous regulation of mammalian neurite development by Notch1 and Delta1. Curr Biol 9:1448-57