Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS038517-03
Application #
6394100
Study Section
Special Emphasis Panel (ZRG1-MDCN-7 (01))
Program Officer
Nichols, Paul L
Project Start
1999-04-19
Project End
2003-03-31
Budget Start
2001-04-01
Budget End
2002-03-31
Support Year
3
Fiscal Year
2001
Total Cost
$172,323
Indirect Cost

  Institution

Name
University of Pennsylvania
Department
Neurology
Type
Schools of Medicine
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104

  Publications

Personius, Kirkwood E; Chang, Qiang; Mentis, George Z et al. (2007) Reduced gap junctional coupling leads to uncorrelated motor neuron firing and precocious neuromuscular synapse elimination. Proc Natl Acad Sci U S A 104:11808-13
Yin, Xinghua; Kidd, Grahame J; Pioro, Erik P et al. (2004) Dysmyelinated lower motor neurons retract and regenerate dysfunctional synaptic terminals. J Neurosci 24:3890-8
Bittman, Kevin S; Panzer, Jessica A; Balice-Gordon, Rita J (2004) Patterns of cell-cell coupling in embryonic spinal cord studied via ballistic delivery of gap-junction-permeable dyes. J Comp Neurol 477:273-85
Su, Yuhua; Balice-Gordon, Rita J; Hess, Darren M et al. (2004) Neurobeachin is essential for neuromuscular synaptic transmission. J Neurosci 24:3627-36
Wyatt, Ryan M; Balice-Gordon, Rita J (2003) Activity-dependent elimination of neuromuscular synapses. J Neurocytol 32:777-94
Personius, Kirkwood E; Balice-Gordon, Rita J (2002) Activity-dependent synaptic plasticity: insights from neuromuscular junctions. Neuroscientist 8:414-22
Personius, K E; Balice-Gordon, R J (2001) Loss of correlated motor neuron activity during synaptic competition at developing neuromuscular synapses. Neuron 31:395-408
Personius, K; Chang, Q; Bittman, K et al. (2001) Gap junctional communication among motor and other neurons shapes patterns of neural activity and synaptic connectivity during development. Cell Commun Adhes 8:329-33
Personius, K E; Balice-Gordon, R J (2000) Activity-dependent editing of neuromuscular synaptic connections. Brain Res Bull 53:513-22
Kopp, D M; Perkel, D J; Balice-Gordon, R J (2000) Disparity in neurotransmitter release probability among competing inputs during neuromuscular synapse elimination. J Neurosci 20:8771-9