Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS038710-04
Application #
6531101
Study Section
Special Emphasis Panel (ZRG1-BDCN-6 (03))
Program Officer
Jacobs, Tom P
Project Start
1999-04-20
Project End
2004-02-29
Budget Start
2002-03-01
Budget End
2004-02-29
Support Year
4
Fiscal Year
2002
Total Cost
$495,938
Indirect Cost
Name
Scripps Research Institute
Department
Type
DUNS #
City
La Jolla
State
CA
Country
United States
Zip Code
92037
Izawa, Yoshikane; Gu, Yu-Huan; Osada, Takashi et al. (2018) ?1-integrin-matrix interactions modulate cerebral microvessel endothelial cell tight junction expression and permeability. J Cereb Blood Flow Metab 38:641-658
Hawkins, Brian Thomas; Gu, Yu-Huan; Izawa, Yoshikane et al. (2015) Dabigatran abrogates brain endothelial cell permeability in response to thrombin. J Cereb Blood Flow Metab 35:985-92
Gu, Yu-Huan; Kanazawa, Masato; Hung, Stephanie Y et al. (2015) Cathepsin L acutely alters microvessel integrity within the neurovascular unit during focal cerebral ischemia. J Cereb Blood Flow Metab 35:1888-900
Emberson, Jonathan; Lees, Kennedy R; Lyden, Patrick et al. (2014) Effect of treatment delay, age, and stroke severity on the effects of intravenous thrombolysis with alteplase for acute ischaemic stroke: a meta-analysis of individual patient data from randomised trials. Lancet 384:1929-35
Wardlaw, Joanna M; Murray, Veronica; Berge, Eivind et al. (2014) Thrombolysis for acute ischaemic stroke. Cochrane Database Syst Rev :CD000213
Sheth, Kevin N; Kimberly, W Taylor; Elm, Jordan J et al. (2014) Exploratory analysis of glyburide as a novel therapy for preventing brain swelling. Neurocrit Care 21:43-51
Kalimo, Hannu; del Zoppo, Gregory J; Paetau, Anders et al. (2013) Polymorphonuclear neutrophil infiltration into ischemic infarctions: myth or truth? Acta Neuropathol 125:313-6
del Zoppo, Gregory J; Izawa, Yoshikane; Hawkins, Brian T (2013) Hemostasis and alterations of the central nervous system. Semin Thromb Hemost 39:856-75
del Zoppo, Gregory J (2013) Plasminogen activators and ischemic stroke: conditions for acute delivery. Semin Thromb Hemost 39:406-25
Hawkins, Brian T; Gu, Yu-Huan; Izawa, Yoshikane et al. (2013) Disruption of dystroglycan-laminin interactions modulates water uptake by astrocytes. Brain Res 1503:89-96

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